Manor Drills - Module 5

Specific quantity of drug product having the uniform character and quantity, produced during a single manufacturing process

a.Lot

b.Batch

c.Product line

d.Bulk

B

Type of parabens that disrupt the endocrine system

a.Methyl

b.Propyl

c.Long-chain

d.Short-chain

C

Also known as compressed lozenges

a.Candies

b.Troches

c.Pastilles

d.Lollipops

B

A type of tablet that dissolves slowly in the cheeks for systemic absorption

a.Chewable tablet

b.Orally disintegrating tablet

c.Buccal tablet

d.Sublingual tablet

C

Lacrimal fluid has an isotonicity values corresponding to that of NaCl solution with the strength of

a.0.1%

b.9.0%

c.1.0%

d.0.9%

D

Burrow's solution is used as

a.Diluent

b.Douche

c.Astringent

d.Mouthwash

C

Gas used in gas sterilization

a.Carbon dioxide

b.Ethylene oxide

c.Butane

d.CFCs

B

Pencil-shaped suppositories

a.Rectal suppositories

b.Vaginal suppositories

c.Urethral suppositories

d.Ocular suppositories

C

Addition of an equal volume of diluent to a potent substance placed in a mortar

a.Spatulation

b.Trituration

c.Geometric dilution

d.Tumbling

C

Describe the flow property of a powder based on the angle of repose if the height of the powder cone is 5.8 cm and the horizontal spread is 20 cm

a.Excellent

b.Good

c.Fair

d.Passable

A

Most widely used milling equipment that uses a high speed rotor to which swinging arms are fixed

a.Roller mill

b.Edge runner mill

c.Ball mill

d.Hammer mill

D

The following are used as disintegrants, except:

a.Gelatin

b.Starch paste

c.Sodium starch glycolate

d.Microcrystalline cellulose

A

Long-acting form or polymorph of insulin

a.Crystalline

b.Amorphous

c.Alpha

d.Beta

A

The required class for compounding area in sterile production

a.Class 100,000

b.Class 10, 000

c.Class 1,000

d.Class 100

D

Most penetrating form of radiation

a.Alpha radiation

b.Beta radiation

c.Gamma radiation

d.Electron radiation

C

It is the policy of the state to safeguard the integrity of its territory and the well-being of its citizenry particularly the youth, from the harmful effects of dangerous drugs.

a.RA 9165

b.RA 8981

c.RA 9994

d.RA 7581

A

Moisture content requirement for soft-gelatin capsules

a.

3 - 6%

b.

6 - 10%

c.

12 - 16%

d.

16 - 20%

B

Part of the tableting machine that guides the movement of punches

a.Hopper

b.Feed shoe

c.Die

d.Cam track

D

Also known as pessaries

a.Rectal suppositories

b.Vaginal suppositories

c.Urethral suppositories

d.Ocular suppositories

B

Formation of paste by addition of non-solvent liquid (Mineral oil in water-soluble substances)

a.Trituration

b.Levigation

c.Pulverization by Intervention

d.Sifting

B

First TDDS developed

a.

Duragesic ®

b.

Androderm ®

c.

Testoderm ®

d.

Transderm Scop ®

D

Compute for the osmotic pressure in atm of a 0.884M of sucrose solution at 16°C

a.25.96 atm

b.25.69 atm

c.20.96 atm

d.52.96 atm

C

Cup and bob viscometer type where the bob is rotated

a.Searle type

b.Couette Type

c.Cone and Plate Type

d.Ostwald Type

A

Hydroalcoholic solutions prepared from vegetable drugs or chemical substances

a.Tinctures

b.Elixirs

c.Spirits

d.Fluid extracts

A

Which example of bulk powder is dissolved in warm water prior to use as cleansing agent or antiseptic for body cavity?

I. Dentifrices

II. Dusting Powders

III. Douche Powders

IV. Insufflations

V. Triturations

a.III

b.V

c.II

d.I

A

The following are Van der Waals forces of attraction, except:

a.Hydrogen bonding

b.Dipole-induced dipole

c.Keesom forces

d.Debye forces

A

Part of transdermal drug delivery system (TDDS) that prevents water and drug loss

a.Occlusive backing film

b.Drug reservoir

c.Adhesive layer

d.Release laye

A

Largest capsule size for human

a.0000

b.000

c.1

d.5

B

To promote, encourage, and require the use of generic terminology of drugs.

a.RA 6675

b.RA 8981

c.RA 9711

d.RA 10918

A

In Stokes law, the parameter that has the greatest effect on the sedimentation rate is:

a.Diameter of the particle

b.Density of the particle

c.Density of the medium

d.Gravity

A

Expanded Senior Citizen Act of 2010

a.RA 9156

b.RA 6675

c.RA 8423

d.RA 9994

D

Hydrophilic ointment is what type of ointment base

a.Hydrocarbon base

b.Absorption base

c.Water-removable base

d.Water-soluble base

C

This is known as heat content and it is the heat required to increase the internal energy and to perform work.

a.Specific heat

b.Heat potential

c.Entropy

d.Enthalpy

D

A type of container that is impervious to air or any other gas

a.Well-closed

b.Tight

c.Hermetic

d.Tamper-resistant

C

Autoclave settings

a.

121°C, 15 psi, 30 - 45 min

b.

121°C, 30 psi, 15 - 20 min

c.

100°C, 15 psi, 15 - 20 min

d.

121°C, 15 psi, 15 - 20 min

D

USP official method of particle size analysis

a.Sieve analysis

b.Optical microscopy

c.Automatic particle counter

d.Sedimentation rate

A

The most preferred method of syrup preparation

a.Solution with heat

b.Solution without heat

c.Reconstitution

d.Percolation

D

Treated soda-lime glass

a.Type I

b.Type II

c.Type III

d.NP

B

Step in sugar coating that adds most weight

a.Sealing

b.Subcoating

c.Syruping

d.Polishing

C

FD&C Red No.40

a.Indigotine

b.Allura Red

c.Erythrosine

d.Tartrazine

B

What manufacturing process is applicable for Hard Gelatin Capsules?

a.Fusion method

b.Pin method

c.Tip Seal Method

d.Rotary Die Process

B

A sweetener that is 500x sweeter than sucrose

a.Acesulfame potassium

b.Aspartame

c.Sucralose

d.Saccharin

D

Flavorant that mask bitter taste of drugs

a.Chocolate

b.Orange

c.Vanilla

d.Butterscotch

A

Most inert grade of mixing tanks

a.SS 316

b.SS 304

c.SS 136

d.SS 403

A

Most recommended rotating shell mixers that can alternately combine and draw apart the raw materials

a.V-shell blender

b.Sigma blade mixer

c.Double-cone blender

d.Planetary mixer

A

Type of manufacturing activity wherein a competent manufacturing company manufactures products of other company

a.Primary manufacturing

b.Secondary manufacturing

c.Tertiary manufacturing

d.Toll manufacturing

D

A type of powder paper that is transparent and water-proof, suitable for deliquescent and hygroscopic drugs

a.Bond paper

b.Glassine

c.Vegetable parchment

d.Wax pape

D

FDA Act of 2009

a.RA 9502

b.RA 7581

c.RA 9711

d.RA 9502

C

The PRC Modernization Act of 2000

a.RA 10912

b.RA 8981

c.RA 8423

d.RA 9711

B

What manufacturing process is applicable for Soft Gelatin Capsules?

a.Tip Seal Method

b.Rotary Die Process

c.Pin method

d.Fusion Method

B

Simple ointment is a mixture of

a.White petrolatum + white wax

b.White petrolatum + yellow wax

c.Yellow petrolatum + white wax

d.Yellow petrolatum + yellow wax

D

Gas law wherein V and T are variable and P, n, R are held constant

a.

Boyle's Law

b.

Charles' Law

c.

Avogadro's Law

d.

Gay-Lussac's Law

B

An emulsion instability which defined as the irreversible separation into a later due to coalescence of the internal phase

a.Sedimentation

b.Creaming

c.Breaking or Cracking

d.Phase inversion

C

Traditional and Alternative Medicine Act of 1997

a.RA 9502

b.RA 8981

c.RA 8423

d.RA 10912

C

Use of Tragacanth in tablet formulation

a.Disintegrant

b.Binder

c.Diluent

d.Lubricant

B

Which example of bulk powder is locally applied non-toxic powders that have no systemic action?

I. Dentifrices

II. Dusting Powders

III. Douche Powders

IV. Insufflations

V. Triturations

a.II

b.III

c.V

d.I

A

Too much of this excipient in the formulation of effervescent granules causes a sticky product

a.Citric acid

b.Tartaric acid

c.Malic acid

d.Fumaric acid

A

Most widely used pressurizable container in aerosols

a.Aluminum

b.Glass

c.Tin-plated steel

d.Brass

C

Range of HLB value in the Griffin scale for anti-foaming agents

a.0-3

b.3-8

c.8-16

d.16-18

A

An automatic particle counter that uses electric resistance to determine the size of the particle

a.HIAC Royco

b.Coulter counter

c.Gelman

d.Abbe

B

Type of extract where nearly all solvent is removed

a.Semiliquid

b.Pilular

c.Powdered

d.Marc

B

The gram-molecular volume of gas at STP is equal to:

a.1.0 L

b.2.24 L

c.22.4 L

d.22.4 mL

C

Which example of bulk powder is blown into a body cavity using a special device?I. DentifricesII. Dusting PowdersIII. Douche PowdersIV. InsufflationsV. Triturations

a.IV

b.III

c.V

d.I

A

The Avogadros number is equal to

a.6.02 x 1023

b.1.802 x 1023

c.9.6 x 1023

d.6.0 x 1023

A

A drug is soluble if its 1 part can be dissolved to

a.Less than 1 part of solvent

b.1 to 10 parts of solvent

c.10 to 30 parts of solvent

d.30 to 100 parts of solvent

C

The ratio of the void volume to the bulk volume of the packing

a.Porosity

b.Packing arrangement

c.Bulkiness

d.Flow particles

A

What manufacturing process is applicable for closing ampules?

a.Wet Granulation Method

b.Pin Method

c.Tip Seal Method

d.Fusion Method

C

Type of tablet defects in which there is a partial or complete separation of the top or bottom crown

a.Lamination

b.Capping

c.Cracking

d.Chipping

B

In optical microscopy, this is the longest tangent line that can be measured in a particle

a.Martin diameter

b.Feret diameter

c.Projected area diameter

d.Longest diameter

B

Generics Act of 1988

a.RA 6675

b.RA 8981

c.RA 9165

d.RA 8203

A

The biological half-life of a drug that is eliminated by 1st order is mathematically represented by:

a.1/k

b.log k

c.0.693/k

d.2.303/k

C

Composition of glycerogelatin

a.40% gelatin, 35% glycerin, 15% water, 10% API

b.45% glycerin, 30% water, 15% gelatin, 10% API

c.40% glycerin, 35% water, 15% gelatin, 10% API

d.45% gelatin, 30% glycerin, 15% water, 10% API

C

The following are considered as true antioxidants, except:

a.Vitamin C

b.Vitamin E

c.BHT

d.BHA

A

Which example of bulk powder is referred to as dilutions of potent powdered drugs?

I. Dentifrices

II. Dusting Powders

III. Douche Powders

IV. Insufflations

V. Triturations

a.IV

b.III

c.V

d.I

C

Required temperature for specific gravity determination

a.15.56°C

b.30°C

c.25°C

d.20°C

C

The intermolecular forces exist between Cl2 and CBr4 are:

a.Dipole-dipole

b.Dipole-induced dipole

c.Induced dipole-induced dipole

d.Ion-induced dipole

C

Using White Vincent Method, compute for the required volume to make 0.3 g of Atropine sulfate (E=0.13) isotonic.

a.3.9 mL

b.4.3 mL

c.25.6 mL

d.33.3 mL

B

Which of the following is a colligative property?

a.Osmotic Pressure

b.Boiling Point

c.Freezing Point

d.Vapor Pressure

A

Preservative used in hard gelatin capsules

a.Parabens

b.Benzyl benzoate

c.Sulfur dioxide

d.Titanium dioxide

C

The dissolution of drug is calculated using

a.Henderson-Hasselbalch

b.Noyes-Whitney

c.Arhhenius

d.Stokes

B

A dispersion system that composed of small inorganic particles and large organic molecules dispensed throughout a liquid vehicle

a.Gel

b.Cream

c.Paste

d.Magma

A

Which manufacturing process is applicable for semisolid dosage forms?

a.Rotary Die Process

b.Wet granulation

c.Tip Seal

d.Fusion Method

D

Reliable sealing method for ampule closure

a.Tip sealing

b.Bead sealing

c.Pull sealing

d.Band sealing

C

Type A hydrolysis of gelatin

a.Acid

b.Base

c.Salt

d.Partial

A

Compute for the E-value of Zinc Chloride (MW=135.9) with an Liso of 5.1.

a.0.46

b.0.64

c.453

d.1.22

B

To have an effective competition policy in the supply and demand of quality drugs. .

a.RA 10918

b.RA 9502

c.RA 8423

d.RA 10912

B

Method of granulation used for moisture- and heat-sensitive drugs

a.Wet granulation

b.Dry granulation

c.Melt granulation

d.Direct compression

B

Storage condition: Cool

a.

-20 to -10°C

b.

2 to 8°C

c.

8 to 15°C

d.

15 to 20°C

C

What manufacturing process is applicable for tablets?

a.Rotary Die Process

b.Wet Granulation

c.Tip Seal Method

d.Fusion Method

B

One of its objectives is to standardize and regulate the pharmacy education in the country.

a.RA 10912

b.RA 10918

c.RA 8203

d.RA 9994

B

Crystal symmetry of Urea

a.Cubic

b.Tetragonal

c.Hexagonal

d.Rhombic

B

Convert 37.5°C to Fahrenheit

a.

98.6 °F

b.

99.5 °F

c.

100.4 °F

d.

100.3 °F

B

To safeguard the health of the people against counterfeit drug.

a.RA 9165

b.RA 8203

c.RA 9994

d.RA 9711

B

The buffer equation is also known as

a.Noyes-Whitney

b.Arrhenius

c.Henderson-Hasselbalch

d.Van't hoff

C

Describe the flow characteristic based on Hausner ratio if the bulk volume is 70 mL and the tapped volume is 60 mL

a.Excellent

b.Good

c.Fair

d.Passable

B

Most stable polymorph of cocoa butter

a.Alpha

b.Beta

c.Beta prime

d.Gamma

B

Type of plastic used in blister packs

a.1

b.2

c.3

d.4

C

Type of extended-release formulation that follows zero-order kinetics

a.Immediate-release

b.Sustained-release

c.Controlled-release

d.Target-release

C

Flow system that shows a yield value

a.Plastic

b.Pseudoplastic

c.Dilatant

d.Newtonian

A

Which example of bulk powder contains a soap, mild abrasive agent and anticariogenic agent?

I. Dentifrices

II. Dusting Powders

III. Douche Powders

IV. Insufflations

V. Triturations

a.V

b.III

c.II

d.I

D