Organic Chemistry Chapter 7

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8 Terms

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Substitution Reaction

Occurs when treated with a nucleophile where the nucleophile replaces the halogen of an alkyl halide

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Elimination Reaction

Occurs when treated with a base where a π bond (an alkene) is formed

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What reagent can function as both a base and nucleophile?

Hydroxide (HO-)

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What is another term for the alkyl halide?

Substrate

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A good leaving group is the conjugate base of…

An acid with a pKa < 0

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Halides such as chloride, bromide, iodide, as well as sulfonate ions (RSO3- ) are examples of…

Good leaving groups

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Which halide is not considered a good leaving group?

Fluoride (pKa of 3.2)

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