L7 Excitable cells skeletal muscle

What is Regeneration in a Wound?

replaces damage tissue with square cell type and returns healthy structure + function

What is Fibrosis in a Wound?

damaged tissue is replaced with a fibrous (scar) tissue mainly collage fibers, some structural restoration but not functional

What is the 1st stage of Wound Healing?

cut blood vessels into the wound, blood clotting factors numerous white blood cells

What is the 2nd stage of Wound Healing?

blood clot forms temporary patching of the wounds, WBCs, cleaning wound of cellular debris

What is the 3td stage of Wound Healing?

blood vessels regen and grow into the wound (granulation tissue = inc blood vessel)

What is the 4th stage of Wound Healing?

regen of epithelial cells, migrate into wounds

What are the Functions of the Skeletal Muscle?

heat production (inc heat production)

body movement (contraction of muscle allows for movement)

maintenance of posture

protection and support

regulating elimination of materials

fuel utilization/storage

What are the different types of Connective Tissue?

epimysium

perimysium

endomysium

What is the Epimysium

surrounds entire muscle (thick layer of dense irregular CT)

What is the Perimysium?

surrounds fascicles

What is the Endomysium?

less dense, delicate layer of CT

What is the size in order of skeletal muscle?

skeletal muscle > fascicles > muscle fibers (muscle cells) > myofilaments 

What are the Functions of Blood Vessels in the Skeletal Muscle?

deliver O₂ + nutrients to working muscle

remove waste products 

What is the path of Blood? 

arteries → arterioles → capillaries → venules → veins

What are the different Nerves in the Skeletal Muscle?

somatic motor nerves

autonomic nerves

What are Somatic motor nerves?

aware of these, can control them, allow for muscle contraction

What are the different Somatic motor nerves?

motor neurons

sensory nuerons

What are Autonomic nerves?

unconscious, not aware of (blood vessels)

What are Myblasts?

cells that develop into muscle fibers

What is the outermost layer of CT associated with skeletal muscle

epimysium

Hemoglobin is known to have ____ storage

dynamic (pockets)

What is the Resting membrane potential in the cytosol?

-70mV

What is the Electrochemical Gradient?

the ability of a cell to respond to a stimulus

Another name for Extracellular fluid is

Interstitial fluid

Another name for Cytosol is 

Intracellular fluid

What happens to the Electrochemical Gradient in the cell when Na⁺ enters through ligand gated channels 

-70mV → -55mV

Voltage gated ion channels open up at what charge?

-55mV

When do K⁺ ions channel open up at

-55mV

What is the purpose of K⁺ leaving the cytosol?

restores membrane potential

What are Na/K pumps?

always open

uses ATP

against gradient

Ca⁺ channels enter the cell through ____ gates

voltage