A quiz over the introduction to biomaterials, including metals, polymers, ceramics, and more.
Biomaterial [Old]
a non-viable material used in a medical device intended to interact with biological systems
Biomaterial [New]
Any material used to make devices to replace a part or a \n function of the body in a safe, reliable, economic, and physiologically acceptable manner.
Synthetic Materials
Metals, polymers, ceramics, composites
Biological Materials
Biopolymers, tissue derived (collagen), tissues
Joint replacements, plates, screws
Titanium, titanium alloys, cobalt-chromium, allografts
Bone replacement/regeneration
Hydroxyapatite, stem cell
Biomaterials outside of medical devices
Biosensors, microfluids, nanofabrication, neural computing
Biomaterials must be…
Biocompatible
Structural properties
Stiffness, area/mass, moment of inertia
Material properties
Elastic modulus, viscoelasticity, fatigue life
Biocompatibility
Acceptance of an artificial implant by the \n surrounding tissues and by the body as a \n whole (doesn’t degrade or degrades without harm)
Biomaterial Selection Criteria
Biocompatibility
Physical & mechanical properties
Biological fixation properties
Easy to make and sterilize
Can function in vivo
Device Performance
Design
Structural requirements
Clinical requirements
Regulatory (FDA)
Processing
Materials selection
Bulk Properties
Tension/compression
Shear/torsion
Bending
Hardness
Surface Properties
Surface roughness
Surface crystallinity
Surface energy (hydrophilicity)
Stress
Force / Area
Strain
Change in length / Original Length
Hooke’s Law
Stress = Modulus * Strain
What does Poisson’s ratio measure?
Resistance to volume change (lateral strain over longitudinal strain)