Med Chem Drug Classes Final

hydrochlorothiazide

Thiazide diuretic

chlorothiazide

Thiazide diuretic

chlorthalidone

Thiazole-like diuretic

metolazone

Thiazole-like diuretic

Furosemide (Lasix)

Type I Loop Diuretic

Torsemeide

Type I Loop Diuretic

Bumetanide

Type I Loop Diuretic

Ethacrynic acid

Type II Loop Diuretic

spirinolactone

Aldosterone blocker

eplernone

Aldosterone blocker

triamterene

ENAC & Na+/K+ -ATPase blocker

amiloride

ENAC & Na+/K+ -ATPase blocker

benzapril

ACE inhibitor

captopril

ACE inhibitor

enalapril

ACE inhibitor

lisinopril

ACE inhibitor

candesartan

Angiotensin receptor blocker (ARB)

losartan

Angiotensin receptor blocker (ARB)

valsartan

Angiotensin receptor blocker (ARB)

Verapamil

Non-dihydropyridine calcium channel blocker

diltiazem

Non-dihydropyridine calcium channel blocker

Amlodipine

Dihydropyridine calcium channel blocker

nicardipine

Dihydropyridine calcium channel blocker

nimodipine

Dihydropyridine calcium channel blocker

nifedipine

Dihydropyridine calcium channel blocker

terazosin

Selective alpha 1 blockers

prazosin

Selective alpha 1 blockers

tamsulosin

Selective alpha 1 blockers

doxazosin

Selective alpha 1 blockers

phenoxybenzamine

Non-selective alpha (both alpha 1 and alpha 2) blockers → binds to allosteric site

phentolamine

Non-selective alpha (both alpha 1 and alpha 2) blockers → binds to active site

timolol

Non-selective (1st generation) Beta blocker (Beta 1 and Beta 2)

propranolol

Non-selective (1st generation) Beta blocker (Beta 1 and Beta 2)

sotalol

Non-selective (1st generation) Beta blocker (Beta 1 and Beta 2)

atenolol

Selective (2nd generation) Beta blocker (Beta 1)

esmolol

Selective (2nd generation) Beta blocker (Beta 1)

metoprolol

Selective (2nd generation) Beta blocker (Beta 1)

acebutolol

Selective (2nd generation) Beta blocker (Beta 1)

bisoprolol

Selective (2nd generation) Beta blocker (Beta 1)

carvedilol

Non-selective (3rd generation) Beta blocker (Beta 1, Beta 2, and Alpha 1)

labetalol

Non-selective (3rd generation) Beta blocker (Beta 1, Beta 2, and Alpha 1)

aspirin

COX1/2 inhibitor

clopidegrel

ADP receptor inhibitor - Thienopyridine derivative -(irreversible)

prasugrel

ADP receptor inhibitor - Thienopyridine derivative -(irreversible)

ticlodipine

ADP receptor inhibitor - Thienopyridine derivative -(irreversible)

ticagrelor

ADP receptor inhibitor - Non-thienopyridine derivative -(reversible)

abciximab

GpIIb/IIIa inhibitor

tirofiban

GpIIb/IIIa inhibitor

eptifibatide

GpIIb/IIIa inhibitor

cilostazol

Phosphodiesterase 3 (PDE3) inhibitor

dipyridamole

Phosphodiesterase 3 (PDE3) inhibitor

warfarin

Vitamin K Epoxide Reductase Inhibitor

Rivaroxiban

Factor Xa inhibitor (low molecular weight heparin)

Fondaparinux

Synthetic form of heparin (low molecular weight heparin), binds to AT-III

escitalopram

Selective serotonin reuptake inhibitor (SSRI)

sertraline

Selective serotonin reuptake inhibitor (SSRI)

paroxetine

Selective serotonin reuptake inhibitor (SSRI)

venlafaxine

Serotonin-norepinephrine reuptake inhibitor (SNRI)

duloxetine

Serotonin-norepinephrine reuptake inhibitor (SNRI)

busiprone

Serotonin receptor agonist

midazolam

Benzodiazepine (short-acting)

triazolam

Benzodiazepine (short-acting)

lorazepam

Benzodiazepine (intermediate-acting)

oxazepam

Benzodiazepine (intermediate-acting)

alprazolam

Benzodiazepine (intermediate-acting)

temazepam

Benzodiazepine (intermediate-acting)

diazepam

Benzodiazepine (long-acting)

chlordiazepoxide

Benzodiazepine (long-acting)

clonazepam

Benzodiazepine (long-acting)

ramelteon

Melatonin receptor agonist

temazepam

Benzodiazepine (particularly for hypnotics)

flurazepam

Benzodiazepine (particularly for hypnotics)

zolpidem

Non-benzodiazepine hypnotic

zaleplon

Non-benzodiazepine hypnotic

eszopiclone

Non-benzodiazepine hypnotic

suvorexant

Orexin receptor antagonist

diphenhydramine

Histamine receptor antagonist

doxepin

Atypical antidepressants (5-HT reuptake & H1/2RA)

mirtazapine

Atypical antidepressant (induces release of 5-HT; maybe H1RA)

trazodone

Atypical antidepressant ((5-HT reuptake & H1RA)

carbamazepine

Na+ channel blocker

oxcarbazepine

Na+ channel blocker

phenytoin

Na+ channel blocker

lamotrigine

Na+ channel blocker

topiramate

Na+ channel blocker

valproate

Na+ channel blocker

ethosuximide

Ca+ channel blocker

gabapentin

Ca+ channel blocker

pregabalin

Ca+ channel blocker

levetiracetam

SV2A blocker

perampanel

AMPA blocker

felbamate

NDMA blocker

ketamine

NDMA blocker

topiramate

GABAa receptor agonist

propofol

GABAa receptor agonist

tiagabine

GABA reuptake inhibitor (focal seizures)

vigabatrin

GABA transaminase antagonist

valproate

GABA transaminase antagonist

rosuvastatin

HMG-CoA reductase inhibitor

atorvastatin

HMG-CoA reductase inhibitor