Hema: Disease Affecting Erythrocytes

microcytic hypochromic

iron deficiency anemia

microcytic hypochromic

B-thalassemia minor & major

microcytic hypochromic

a-thalassemia minor & major

macrocytic normochromic

nonmegaloblastic anemia

macrocytic normochromic

megaloblastic anemia

normocytic normochromic

aplastic anemia

normocytic normochromic

immune hemolytic anemia

normocytic normochromic

hemolytic disease of the fetus & newborn

normocytic normochromic

hereditary spherocytosis

normocytic normochromic

hereditary elliptocytosis

normocytic normochromic

microangiopathic hemolytic anemia

normocytic normochromic

hemoglobin CC disease

normocytic normochromic

hemoglobin SS disease

normocytic normochromic

hemoglobin SC disease

iron deficiency anemia

• hypochromic & microcytic

• large variation in size

• possible thrombocytosis

B-thalassemia minor

• microcytosis, slight hypochromia

• target cells, basophilic stippling

basophilic stippling

its presence is common in thalassemia minor but not in IDA

B-thalassemia major

• marked variation in size & shape

• numerous nucleated erythrocytes

• microcytic, hypochromic

• target cells, basophilic stippling

• teardrop cells, schistocytes, polychromasia

a-thalassemia minor

• microcytic, hypochromic

• marked poikilocytosis

• target cells

• polychromasia

a-thalassemia major

Hemoglobin Bart Hydrops Fetalis Syndrome

a-thalassemia major

• numerous nucleated erythrocytes

• marked variation in size

• hypochromia, variable polychromasia, macrocytes

nonmegaloblastic anemia

• round macrocytes

• normal leukocyte & platelet counts

megaloblastic anemia

• pancytopenia