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PRRs
Pattern Recognition Receptors, secrete cytokines which activate T and B cells, can be found membrane-bound or cytoplasmic
Clonal
Refers to “one type”, especially in cell receptors, displayed in all cells that encounter antigens
PAMP
Pathogen associated molecular pattern
MAMP
Microbe associated molecular pattern
DAMP
Damage associated molecular pattern
Toll-like receptor (TLR)
found in plasma membrane, endosomes, lysosomes
C-type lectin receptor (CLR)
found in plasma membrane
Retinoic acid-inducible gene-I (Rig-I)-like receptor (RLR)
found in cytosol
Nucleotide oligomerization domain (NOD)-like receptor
found in cytosol
Absent-in-melanoma (AIM)-like receptor (ALR)
found in cytosol and nucleus