Week 9: Microscopic Anatomy of the Liver

liver

functions in blood filtration, blood detoxification, gluconeogenesis, bile production, etc.

right, left, caudate, quadrate

four lobes of the liver

hepatic arteries, hepatic portal vein

how the liver recieves blood

hepatic veins

drains blood from the liver

hepatic lobule

structural unit of the liver; hexagonal shape with portal triads in each corner and a central vein in the center

hepatocytes

compose the bulk of the liver; function in detoxification, gluconeogenesis, and bile production

hepatic portal triad

group of three vessels at each order of a given lobule

hepatic arteriorles

carry oxygenated blood from the hepatic artery to liver cells; part of the portal triad

hepatic venules

carry blood from the hepatic portal vein to liver cells; part of the portial triad

bile ducts

collect bile from hepatocytes; part of the portal tirad

sinusoids

cavities where blood from the hepatic arteriole and hepatic venule mix; characterized by:

-large gaps between endothelial cells

-incomplete basement membrane

-space of Disse separating hepatocytes from sinusoids

space of Disse

space separating hepatocytes from sinusoids

central vein

collects blood from sinusoids

canaliculi

channels between hepatocytes that transport bile produced within the hepatocytes to bile ducts

hepatic venule/arteriole

sinusoid

central vein

hepatic veins

inferior vena cava

blood flow through the liver

hepatocyte

canaliculi

bile ducts

biliary system

movement of bile through liver