Aspirin

Drug class

Antiplatelet

Pharmacology

Inhibits platelet aggregation .

Indication

Suspected ACS, Acute cardiogenic pulmonary oedema

Contraindications

Allergy/ADR to aspirin or NSAID, Bleeding or clotting disorders, Current GI bleeding or peptic ulcers, Patient less than 18 yrs

Presentation

tablet (white), 300 mg aspirin

Onset

10 minutes

Duration

1 week

Half-life

3.2 hours (300-650 mg)

Schedule

S2 therapeutic poison

Routes

PO

Precautions

Possible aortic aneurysm or other conditions that may require surgery, pregnancy, Hx GI bledding or peptic ulcers, concurrent anticoagulant therapy

Side effects

epigastric pain/discomfort, nausea/vomiting, gastritis, GI bleeding, NSAID induced bronchospasms.

Adult Dose

300 mg chewed and followed by small sip of water (where possible).