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BONE
Highly specialized connective tissue composed of branching cells calcified in an organic osteoid matrix
BONE
Composed of cells, calcium, water, collagen and proteins
Constantly undergoes destruction and regeneration
Living tissue
Osteoblast
reproduce new bone formation
faster: leads to osteosclerosis
Osteoclast
bone resorption
faster: leads to osteoporosis
Osteocyte
Living element of bone 🡪 nutrients
Matured osteoblast
Regulates flow of minerals into and out of bone
Organic
Collagen type 1
20%
Inorganic
Hydroxyapatite: contains phosphates and carbonates
70%
Membranous Stage
Gradual replacement of tissue into osteoid matrix
Bones: head and face
Osteoid matrix
Early stages of bone
Structural framework
Undergo calcification 🡪 deposition of calcium in the bones (solidify bones)
Endochondral Stage
Cartilage
Mesenchymal cells
Endochondral Stage
Cartilage destroyed will turn into bone
Bones:
Sternum
Ribs
Scapula
Spine
Pelvis
Long bones
Haversian System
Aka: Osteones
Long patent columns that are irregularly parallel along the axis of the shaft of bones
Haversian Canals
surround the lamellae
central spaces located in between haversian system
blood vessels
Lamellae
concentric layers or intercellular substances that surrounds the canal
Lacunae
spaces in between lamellae
osteocytes
processes of osteophytes
Canaliculi
links the lacunae
processes of osteocytes
Volkman’s Canal
transverse/oblique channels connecting osteons
blood supply into bone
Long bones
Type of bones
Length is greater than width
Cylinder-like
Extremities
Short bones
Type of bones
Cuboidal in shape
Length and width are almost equal
Carpals, tarsals
Sesamoid bones
Type of bones
Sesame, small, round shape
Patella, pisiform
Flat bones
Type of bones
Flat, thin, curved
2 compact bones, spongey in between
Sternum, scapula, cranial bones
Complex bones
Type of bones
Irregular or no definite shape
Facial bones, vertebrae, pelvis
Medullary canal
Houses bone marrow (RBC) covered by endosteum
Innermost
Hollow space
surrounded by diaphysis
Endosteum
Surrounds medullary canal
Diaphysis
Shaft/compact of bone
Periosteum
Covering of diaphysis
Metaphysis & Epiphysis
Separated by epiphyseal plate (Cartilaginous/growth plate) at birth
At the ends of long bones
Cancellous bones
Salter Harris Classification
Classification system for log bones
Grade 1
Salter-Harris Grade
Epiphyseal plate
Incomplete fracture of EP
Simple/Surrounding
Grade 2
Salter-Harris Grade
Epiphyseal plate + Metaphysis
Triangular segment of metaphysis
Above
Grade 3
Salter-Harris Grade
Epiphyseal plate + epiphysis
Lower
Grade 4
Salter-Harris Grade
Epiphyseal plate + epiphysis + metaphysis
Through = growth arrest
Grade 5
Salter-Harris Grade
Crushed epiphyseal plate
Rammed comminuted
Fracture
Break/discontinuity of bone
Open Fracture
Compound
(+) wound 🡪 prone to infection
Communicating with surrounding tissue
Gustilo-Anderson Classification
Closed fracture
Simple
(-) wound / skin break
(+) abrasion, contusions
Tscherne Classification
Grade 1
Gustilo Anderson Classification
<1 cm wound
Transverse, oblique
Grade 2
Gustilo Anderson Classification
1 - 10 cm wound
Comminuted type
Grade 3
Gustilo Anderson Classification
>10 cm wound
MVA, muscle, skin, blood vessel
Grade 3a
Gustilo Anderson Classification
Periosteal stripping
Soft tissue injury/laceration
Grade 3b
Gustilo Anderson Classification
Soft tissue injury
Bony coverage
Require flap
Grade 3c
Gustilo Anderson Classification
Blood vessel, circulatory
No transmission of nutrients
Transverse
Type of Fracture
horizontal
forms right angle along axis of bone
Oblique
Type of Fracture
diagonal / slanted
transfixion screw
Spiral
Type of Fracture
Secondary to torsional force (twist mechanism of injury)
fastest to heal
Comminuted
Type of Fracture
bones are broken into several fragments
Segmental
Type of Fracture
bones are broken into several segments
long bones
multifracture
Impacted
Type of Fracture
most stable
GH & Hip joints
Stress
Type of Fracture
secondary to microtrauma / repetitive trauma
Compression
Type of Fracture
axial loading
avulsion
Type of Fracture
strong pull of muscle
Pathological
Type of Fracture
underlying disease
pott’s disease
osteomyelitis
dead bone: sequestrum
healthy bone: involucrum
Supracondylar fracture of Humerus
mc complication: Volkman’s Ischemic contracture
Myositis ossificans
cubitus valgus* / varus deformities
Colle’s fracture
dorsal of distal radius
MOI: FOOSH
Dinner / Silver fork
Poteau’s fracture
Smith’s fracture
ventral of distal radius
MOI: FOBOTH / Fall on flexed hand
Garden spade deformity
Reverse Colle’s Fx
Montegia
Types 3, 2, 1, 4
fracture of ulna with radial head dislocation
types:
_ - lateral / anterolateral d/L
_ - posterior d/L
_ - anterior d/L
_ - ulna & radius
Galeazzi
fracture of radius with ulnar head d/L
Aka:
reverse montegia
piedmont fx
dupuytren’s fx
fx of necessity
Nightstick
fracture at the shaft of ulna
Greenstick
common in children
fracture at the bones of forearm
affects pronation/supination
Barton
fracture at the wrist
Chauffer’s fx
fracture at the radial styloid process
Bennet’s fx
fracture at the 1st MCP
avulsion
Gutter splint = > 40 degrees
Rolando
Comminuted fracture at the 1st MCP
comminuted bennet
Boxer’s fx
fracture at the neck of 5th MCP
strip/fist fighter’s fx
Femoral neck fx
LE Fx
crucial blood supply
LCPD
Intertrochanteric
fracture at the greater/ lesser trochanters
Subtrochanteric
fracture proximal to the trochanter/s
Duverney’s fx
fracture at the iliac wing
Straddle’s
double vertical fx of the pubis
horseback
Walther’s fx
fracture at the ischioacetabular of pelvis
Cotton
fracture at the transmalleolar of ankle
inversion/eversion
Nutcracker
fracture at the nut-shaped tarsals → calcaneus & cuboid
March
stress at the 2nd metatarsal shaft
Jones fx
fracture at the 5th metatarsal base
sheperd’s
fracture at the lateral tubercle of talus
Grade 1
Garden classification
Incomplete
Femoral neck fx
Grade 2
Garden classification
complete
undisplaced
Grade 3
Garden classification
complete
partially displaced → <50%
Grade 4
Garden classification
complete
fully displaced → >50%
I
Le Fort Classification
low maxillary / transverse fx of maxilla
II
Le Fort Classification
Pyramidal fx
(+) nasal bridge & maxilla
III
Le Fort Classification
Craniofacial dysjunction/separation
zygomatic arch + inferior orbital
C1: Jefferson Fx
Atypical
compression → axial loading
burst fx at the ring of atlas
C2: Hangman’s Fx
Atypical
Neural arch of the axis
Dens / Odontoid process → Teardrop fx
C7: Clay Shoveller’s Fx
Atypical
vertebra prominence
tip of spinous process of c7
Chance fx
Atypical
secondary to tight seatbelts
thoracic and lumbar
I. Inflammatory
Stages of bone healing
directly occurring after injury
hematoma formation → bruising
prostaglandin mediation → pain
activation of fibroblast
II. Reparative
Stages of bone healing
bulk of fibroblastic activity → repair damages
soft/hard callus formation
III. Remodelling
Stages of bone healing
longest phase
Reversal
Quiescence
Activation
Formation
Resorption
Remodeling stage of bone healing
_ - osteoblast
_ - bone will undergo dormancy
_ - osteoclast
_ - osteoblast will form a new bone
_ - osteoclast will destroy the bone
Reduction
replacement of bones to as near anatomic position as possible
manipulation
Malunion
union of bones in a faulty position/posture
Delayed union
union of bones beyond expected time
UE: 3-12 wks healing
LE: 12-18 wks healing
Non-union
failure of bones to unite
Achondroplasia
mc form of dwarfism
endochondral ossification retardation
autosomal-dominant
disproportionate limbs and trunk
brachycephalic head
Achondroplasia
< 4ft
small face in relation to head
flattened nose & depressed nose bridge
prominent jaw
short and pudgy fingers
Main En Trident
Pseuodochrondoplasia
Metaphyseal chondroplasia
Achondroplasia variant/s
_ - abnormality’s not obvious at birth
_ - similar to ricket’s disease → vit. D deficiency
diastrophic dwarfism
hypochondroplasia
Achondroplasia variant/s
_ - kyphoscoliosis, club foot deformity, proximal set hitchhiker’s thumb
_ - small/milder form of Achondroplasia
chondroectodermal dysplasia
chondrodysplasia punctata
Achondroplasia variant/s
_ - stippled epiphysis
_ - displastic fingernails, polydactyly, distal shortening of legs and forearm
Osteoporosis
silent disease
-2.5 standard deviation of bone mass density