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Metabolism
Sum of cellular chemical reactions
Exergonic Reactions
Reactants have more free energy than products
Endergonic Reactions
Products have more free energy than reactants
ATP
Can transform into ADP + P and back again through synthesis and hydrolysis
ATP Synthesis
Process of creating ATP from ADP + P (usually associated with catabolism)
ATP Hydrolysis
Reaction when a water molecule breaks the bond of ATP, releasing a burst of energy (associated with anabolism)
Coupled Reactions
Energy released by exergonic reaction drives endergonic reaction
Metabolic Pathways
Reactions occur in a sequence which results in products of an earlier reaction becoming the reactants of a later reaction
Enzymes
Proteins that speed up chemical reactions by reducing amount of activation energy + bring substrates into contact with one another
Substrate
Specific molecule an enzyme binds to which is then converted to a product in a chemical reaction
Active Site
A specific region on an enzyme’s surface where a substrate binds and a chemical reaction occurs
Lock and Key Model
Suggests that an enzyme’s active site (lock) fits perfect with the shape of a specific substrate (key)
Enzyme Specificity
The ability of an enzyme to selectively bind to and catalyze a reaction for a specific substrate or group of similar substrates
What are reaction rates affected by?
Enzyme concentration, substrate concentration, temp, pH, denaturation, coenzymes, and inhibitors
Enzyme Inhibitors
Inhibitor binds to the active site of the enzyme, competing with the substrate and reducing the rate of reaction (ex: herbicides and drugs)
Coenzymes
Helper molecules for enzymes to catalyze biochemical reactions
Redox Reaction
One substance loses an electron (oxidation) while the other gains an electron (reduction) and both must occur simultaneously