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is an illness caused by an infectious agent or its toxic products that are transmitted directly or indirectly from one person to another through an agency vector or inanimate object'
Communicable disease
disease that is easily transmitted from one person to another through direct or indirect contact
contagious disease
disease that is transmitted not only by direct contact but requires direct inoculation of the organism through a break on the skin /mucous membrane
infectious disease
is a condition caused by the entry and multiplication of pathogenic microorganisms within the host resulting to signs and symptoms as well as immunologic response.
infection
it is an invasion of organisms (bacteria, helminths, fungi, parasite, and prion)
infection
Destruction of pathogenic organism outside the body by directly applying physical and chemical means
disinfection
types of disinfection
concurrent, terminal, prophylactic
done immediately after individual discharges infectious material or secretions
concurrent disinfection
disinfection used where patient is still the source of infection
concurrent disinfection
applied when patient is no longer the source of infection
terminal disinfection
preventive measures to prevent the spread of infections
prophylactic disinfections
disease that occurs occasionally and irregularly with no specific pattern
sporadic disease
constantly present in a population, country or community
endemic disease
patient acquire the disease in a relatively short period of time'; greater than normal of cases in an area within short period of time
epidemic
disease that occurs worldwide
pandemic disease
classification of disease based on occurence
sporadic, endemic, epidemic, pandemic
develops rapidly ( rapid onset) but asts only short of time
acute disease
develops more slowly (insidious onset) disease likely to be continual or recurrent for long periods
chronic disease
intermediate between acute and chronic disease
subacute disease
causative agent remains inactive for a time but then becomes active to produce symptoms of the disease
latent disease
classification of disease based on severity/ duration of disease
acute, subacute, chronic, latent
Microbes invade a relatively small area of the body
local infection
spread thorughout the body by blood or lymph
generalized (systemic) infection
local infection that spread but are confined to specific areas of the body
focal infection
classfication based on extent of affected hsot body
local infection, generalized infection, focal infection
acute infection that causes the initial illness
primary infection
one caued by an opportunistic pathogen after primary infection has weakened the body’s defenses
secondary infection
does not cause any noticeable infection
subclinical (inapparent infection)
classification of state of host resistance
primary infection, secondary infection, subclinical /inapparent infection
time interval between the initial infection and the 1st appearance of any signs and symptoms'; patient is not yet aware of the disease
incubation period
early, mild appearance of symptoms of the disease
prodromal period
time of greatest symptomatic experience (pt. is sick), overt signs n symptoms of disease, WBC may increase or decrease, can result to death if immune response or medical intervention fails
period of illness
signs n symptoms subside, pathogen replication is brough under control, vulnerable to secondary infection
period of decline
replicaiton of pathogenic is stopped, regains strength and the body returns to its pre diseased stat recovery has occured
period of convalescence
Stages of disease
incubation period, prodomal period, period of illness, period of decline, period of convalescence
capable of transmitting pathogens during the incubation period
incubation carrier
transmit disease during convalescence or recovery period
convalescence carrier
completely recovered from disease but continue to harbor pathogen indefinitely
active carrier
carry pathogen without ever having the disease
passive carrier
types of carrier
incubation carrier, convalescence carrier, active carrier, passive carrier
ability to cause disease
pathogenicity
sufficient number of microorganisms needed to initiate infection
infective dose
disease severity
virulence
ability to enter and move through tissue
invasiveness of microorganisms
conditions that affect infection development
pathogenicity
virulence and invasiveness of
microorganisms
infective dose
organisms specificity
resistance of host
immunity of host
infection control: 1st line of defense n most important practice preventing infection.
hand hygiene
single most important way of preventing transfer of microorganisms
hand washing
condition of being secure against any particular disease, particularly the power which a living organisms possesses to resist and overcome infection
immunity
the resistance that and individual has against disease
immunity
protection against infective or allergic diseases by a system of antibodies, immunoglobins and related resistance factors
immune system
specific immune substance produced by the lymphocytes of the blood and tissue juices of man or animal in response to the introduction into the body of an antigen
antibody
triggering agent of the immune system
antigen
foreign substance introduced into the body causing to produce antibodies
antigen
types of antigen
inactivated (killed organism), attenuated (live weakened organism)
an antigen, not long-lasting, multiple doses needed, booster dose needed
inactivated
single dose needed, long lasting immunity
attenuated
types of immunity
natural, acquired
innate; within the host immune system immunity
natural
outside the host immunity
acquired
2 types of acquired immunity
natural, artificial
through exposure or diseases; had the disease & recovered
natural active
maternal antibodies; acquired through placental transfer
natural passive
introduction of antigen = gives long immunity- months to years
artificial active
introduction of antibodies = gives short immunity- 3-4 weeks
artificial passive
is the induction of introduction of specific protective antibodies in a susceptible person or animal, or the production of cellular immunity in such a person or animal
immunization