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Flashcards covering key terms and concepts related to the microscopic anatomy of skeletal muscle and the sliding filament model.
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Sarcolemma
The plasma membrane of a muscle fiber.
Sarcoplasm
The cytoplasm of a muscle fiber.
Myofibrils
Densely packed rodlike elements within a muscle fiber.
Sarcomere
The smallest contractile unit of a muscle fiber.
A bands
Dark regions in skeletal muscle where thick and thin filaments overlap.
I bands
Light regions in skeletal muscle that contain only thin filaments.
H zone
The lighter region in the middle of the A band.
Z disc (line)
A sheet of proteins in the midline of the I band that holds myofilaments in alignment.
Actin
A protein that makes up thin myofilaments.
Myosin
A protein that makes up thick myofilaments.
Cross bridges
Links formed between myosin heads and actin during muscle contraction.
Tropomyosin
A regulatory protein that blocks myosin binding sites on actin.
Troponin
A regulatory protein that has Ca2+ binding sites, helping to control muscle contraction.
Sarcoplasmic reticulum (SR)
A network that regulates intracellular Ca2+ levels in muscle fibers.
T tubules
Protrusions of the sarcolemma that allow electrical nerve transmissions to reach deep into each muscle fiber.
Sliding filament model
The theory that actin and myosin slide past each other during muscle contraction, resulting in sarcomere shortening.
Power stroke
The process where the myosin head pivots and pulls the actin filament toward the center of the sarcomere during contraction.