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Non-sterile compounding
the compounding process that does not require sterility, which is used to prepare prescriptions for creams, ointments, capsules, oral liquids, etc.
Non-sterile compounding follows guidelines from ____ ____
USP <795>
During non-sterile compounding, rotate the stock to make sure the _____ stock gets used first
oldest
Equipment should be cleaned __________ after compounding to prevent cross-contamination
immediately
Which balance should be used for weighing during prescription compound?
The Class A balance
The Class A balance has a minimum sensitivity of ______ and a maximum capacity of ______
6 mg; 120 g
Which scale is preferred?
a digital scale
Beyond-use date (BUD)
the date after which a compounded medication should not be used (the expiration date and BUD are not the same)
Who assigns expiration dates?
the manufacturers
What is the maximum beyond-use date for non-aqueous compounded products?
6 months
What is the maximum beyond-use date for topical/dermal compounded products that contain water?
30 days
What is the maximum beyond-use date for oral formulations that contain water?
14 days (refrigerated)
Spatulation
the technique of mixing powders an semi-solids (ointments, creams, etc.) on an ointment slab using a spatula
Trituration
reducing the particle size of a substance by grinding it using a mortar and pestle
Levigation
decreasing the surface tension between two ingredients by wetting them with a small amount of insoluble liquid, then spatula ting or triturating
The avoirdupois system
the traditional system of weights os measures in the United States based on pounds (lbs) and ounces (oz)
The metric system
the standard measurement system around the world due to its accuracy and simplicity
1 milligram (mg) = ____ micrograms (mcg)
1,000
1 gram (g) = ____ milligrams (mg)
1,000
1 kilogram (kg) = ____ grams (g)
1,000
1 kilogram (kg) = ___ pounds (lbs)
2.2
1 milliliter (mL) = __ cm³ (cc)
1
1 deciliter (dL) = ___ mL
100
1 liter (L) = ____ mL
1,000
1 ounce (oz) = __ mL
30
1 tablespoon (tbsp) = __ mL
15
1 teaspoonful (tsp) = __ mL
5
1 tbsp = __ tsp
3
I
1
II
2
III
3
IV
4
V
5
VI
6
VII
7
VIII
8
IX
9
X
10
L
50
C
100
D
500
M
1,000
PO
by mouth
PR
rectally
AU
both ears
AS
left ear
AD
right ear
OU
both eyes
OS
left eye
OD
right eye
IV
intravenous
IVPB
intravenous piggyback
IM
intramuscular
ID
intradermal
NG
nasogastric
SC or SQ
subcutaneous
SL
sublingual
TD
transdermal
QD
daily
QOD
every other day
BID
twice daily
TID
three times daily
QID
four times daily
QAM
every morning
QPM
every evening
Qwk
every week
HS
at bedtime
AC
before meals
PC
after meals
PRN
as needed
STAT
immediately
%W/W (percent weight/weight)
the active drug and the inactive base are both in the same unit of weight (grams)
1% = 1 g of active ingredient per 100 g of total product (1% = 1g/100g)
%V/V (percent volume/volume)
the active drug and the inactive base are both in the same unit of volume (milliliters)
1% = 1 mL of active ingredient per 100 mL of total product (1% = 1mL/100mL)
%W/V (percent weight/volume)
the active drug is in the unit of weight (grams), and the inactive base is in the unit of volume (milliliters)
1% = 1 g of active ingredient per 100 mL of total product (1% = 1g/100mL)