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Homeostasis
Balance in the body's internal environment
Living organisms respond to...
stimuli
5 physically relevant ions
Na, K, Mg, Ca, Cl
What happens if you change form of protein
changes the function of it
X Ray
Electromagnetic radiation moves through body and is exposed on photographic plate; creates radiograph
Ultrasound
sound waves pass into body and bounce back to receiver; visualizes as a sonogram
angiography
similar to CT scan but uses a radiopaque dye to enhance differences in areas
-used to check blood vessels
-blood vessels do no show up in X-rays
MRI
radio waves
How to read an X ray
if dense = white
air = black
grey = other structures, depending on density
Radiograph
flat 2D image
-XRAY
ultrasound detects gender
between 16 and 22 weeks of pregnancy
Lithotripsy
ultrasound waves are used to break the kidney stone into smaller pieces, which can pass out with the urine
Ultrasound used for many reasons
-view ovaries and uterus during pregnancy and monitor baby's health
-diagnose gallbladder disease
-evaluate blood flow
-guide needle for biopsy or tumor
-examine breast lump
-check thyroid gland
-find genital and prostate problems
PET
metabolic states of various tissues
pathology
structural and functional changes caused by disease
structural level of organization
chemical level --> cell level --> tissue --> organ
tissue
groups of similar cells and the materials surrounding them
Types of Tissues
Epithelial, connective, muscular, nervous
Which tissues have RMP?
ALL four of them
RMP
resting membrane potential - difference in charge across membrane
integumentary system
skin = largest organ = defense
is epidermis living
NOT living
Skeletal system
consists of bones (source of Ca++ and blood cells - marrow cavities x 2)
Muscular system
ONLY voluntary one that has outward manifestation
-produces body heat, posture, body movements
Hemodynamics
blood flow changes - blood flow to skin
nervous system
input of info --> processing (CNS) --> output
Prefrontal cortices
think and reason & cause and effect
COGNITION
Endocrine system
INTO blood = HORMONES
influences metabolism
why are hormones more effective than neurotransmitters
HIGHER number of numbers
Lympatic system
picks up extra fluid! ALWAYS LEAKING
removes foreign substances from blood and lymph, combats disease, maintain tissue fluid balance
relationship between pH and CO2
Inverse! one up, other down
Medulla
-respiration rate
-heart rate
-blood pressure
Relationship between skeletal muscle and BMR
direct! one increases other increases
bigger muscle, testosterone goes up
Metabolism
ability to use used energy to perform vital functions; all chemical reactions of body
Responsiveness
ability to sense changes in interior and exterior environment and adjust
Physiology about...
ranges
effector
generates the response which can change the value of variable
receptor
monitors value of some variable by detecting a stimulus (change in variable)
Examples of Negative Feedback
-temperature regulation
-blood pressure during exercise
Secretion vs Excretion
Secretion: good! body makes something and sends it out
Excretion: waste
Body Temp Feedback System
- Vasoconstrictions when we're COLD; decrease blood flow to skin to minimize heat loss
- Flushing when hot: blood vessels widen to cool down body
Baroreceptors
detect pressur
Pressure feed back system during exercise
standing up decreases pressure, not receiving blood to brain, HEADH RUSH
when exercising: heart rate increase, blood vessels constrict, increase resistance
Positive Feedback
Labor!
Pressure begins to mount of baroreceptors of cervix: releases oxytocin and uterus contracts, putting more pressure on cervix
Anterior and Posterior
ventral and dorsal
Body Cavities
1.Cranial cavity
2. vertebral cavity
3. thoracic cavity
4. abdominopelvic cavity
What four questions do you use?
1. What made of?
2.What does it look like?
3. What does it look like when it doesn't function correctly?
4.Treatment?
Serous membranes
secrete lubricant --> less friction
covers organs of body cavities and lines cavity
Visceral serous
COVERS the organ
parietal serous
lines the cavity
Pleura
lung
pericardium
around heart
Peritoneum
around internal, abdominal organs
Lose pressure inter plural space
collapsed lung
mesentery
regions of double folded visceral peritoneum that is attached to certain points to the posterior abdominopelvic wall
-whitish layer around organs in abdominal cavity
Transitional Epithelium
stretches and expands - ureter - goes back to original state
Biopsy
removal of tissues for diagnostic purposes
Embryonic germ layers (3)
endoderm, mesoderm, ectoderm
endoderm
forms GI tract
mesoderm
muscle, bone, blood vessels
ectoderm
forms skin and neuroectoderm
Avascular
materials must move by diffusion from underlying connective tissue
how many cell lengths away can obtain enough oxygen from capillary?
6-8 cell lengths
Endothelial
blood and lymphatic vessels
Apical surface
free surface
Goblet cells
secrete mucus
Carcinoma
cancer of epithelial tissue
Ureter vs urethra
ureter: 2 f them - kidney down to bladder
urethra: where pee comes out
Cilia
move mucus across surface of cells
Mucocilitary escalator
- Mucociliary escalator: respiratory tree = trachea and bronchi
- Trap impurities with mucus, cilia beat up (phlegm)
Desmosomes
often found in areas that are subjected to stress - consists of an especially adhesive material between cells
gap junctions
share cytoplasm AND ions
endocrine vs exocrine
endocrine: no open contact with exterior, no ducts; extensive network of blood vessels; produce hormones
exocrine: open contact maintained with exterior by way of ducts that open onto free surface of epithelium
GI, liver, and colon
part of EXOCRINE
Cystic Fibrosis
build up of mucus - issue with goblet cells
autosomal recessive disorder with issues of Cl- ion
Integral proteins
channels, carriers, pumps, receptors
Morbidity
medical condition
Vommitting/diarrhea
dehydration - issues with ions
Merocrine
(standard) exocytosis
Apocrine
pinches off fragments of gland cells; mammary glands and ceruminous glands
Holocrine glands
shedding of entire cells; sebaceous glands (ex: sebaceous glands
Sebum
oil clogs pores - inflammatory and white blood cells increase
most commonly broken bone
clavicle
tendon
strain
bone to muscle
ligament
sprain
bone to bone
achilles/cracanial tendon
largest tendon
what connects to achilles tendon
planters, gastrocnemius, soleous
osteoblast
build bone
osteocytes
mature bone cells, maintain it
osteoclasts
break it down (cleave it)
mast cell
produces inflammation, type of white blood cell; releases histamine in response to injury
white blood cells
leukocytes
respond to injury or infection
Platelets
fragments of hematopoietic cells involved in clotting - thrombocytes - NOT cells
collagen
most common protein in body - strong, flexible
reticular
fills spaces between tissues and organs
elastic
returns to its original shape after dissension or compression
hyaluronic acid
good lubricant - help retain water in skin - helps skin stretch - prevents wrinkles
three types of cartilage
hyaline, fibrocartilage, elastic
mammary vs breast glands
primates: breast
all mammals: mammary gland
cartilage heals slowly because...
avascular and no nerve supply