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How is biological sex defined across living organisms (not just humans)? What core
biological criteria are used to classify an individual (across species) as one sex or another?
.
How many distinct sexes exist in nature? Support your answer with explanations and
examples from multiple types of organisms.
,
What is the default developmental pathway of a human embryo at the moment of conception?
b
What is the SRY gene, where is it located, and what role does it play in human sex
determination?
g
What happens when a person is born with an atypical number of sex chromosomes? For each major syndrome, identify the chromosomal composition, its cause, and its effects on
Phenotype.
b
What sex-determination systems exist in nature beyond the human XX/XY model? For each
system, describe how sex is determined and provide at least one example organism.
g
How do incomplete dominance and codominance each challenge the assumptions of
Mendelian inheritance? What makes them distinct from each other? For both incomplete
dominance and codominance, how do the genotypic and phenotypic ratios compare to
Mendel’s predictions?
g
. Define sex-influenced and sex-limited traits. How does each differ from sex-linked traits in
terms of chromosomal location and expression patterns? How do the genotypic and
phenotypic ratios of sex-influenced and sex-limited traits deviate from standard Mendelian
predictions? Provide examples for each.
g
What are lethal alleles? Explain how they arise and how they distort expected genotypic and
phenotypic ratios in a cross.
f
Distinguish between penetrance and expressivity. How does each concept explain why
individuals with the same genotype can look different? How do they modify expected
Mendelian ratios? Give examples of each.
g
In your own words, what is epistasis, and how is it fundamentally different from simple
dominance? Identify and describe at least three types of epistasis, providing an example for
each.
g
How do environmental factors interact with an organism’s genotype to shape its
phenotype? Choose at least two specific traits and explain the environmental influence on
each.
g