* AP comes down the axon to the axon terminal
* A vesicle full of neurotransmitters releases them into the synaptic cleft
* Neurotransmitters drift across the gap and bind to a receptor
* AP is passed onto the next neuron
* Some of the neurotransmitters are degraded by enzymes, others are carried back to the pre-synaptic neuron by transporter proteins- called reuptake