DEFINITION OF TERMS

PHARMACOLOGY

study of drugs

PHARMACOLOGY

biological and physiologic aspects of drug effects, including ADME, toxicity, and specific MOA of drugs

DRUGS

“PHARMAKON” means

DRUG

substance that affects a biological system in a potentially useful way

DRUG

Any agent that has the ability to modify (alter) the body structure and function agents used in the medication, diagnosis, prevention, treatment and cure of disease in man or other animals (USP)

POISON

any chemical agent that produces harmful effect (eg. Arsenic or Lead)

TOXIN

poison of biological origin (tetrodotoxin)

PHARMACODYNAMICS

”what drugs do to the body”

PHARMACODYNAMICS

mechanism of action of drugs (MOA)

PHARMACOKINETICS

“what the body does to drugs”

PHARMACOKINETICS

Absorption, Distribution, Metabolism, Excretion

PHARMACOTHERAPEUTICS

defined as the study of the rational drug use in the management of diseases

PHARMACEUTICS

“what the pharmacists drugs do to the drugs”

PHARMACEUTICS

involves preparation of dosage forms of drug

PHARMACOGENETICS

genetic influences on responses to drugs

PHARMACOGENOMICS

branch of pharmacogenetics

PHARMACOGENOMICS

the relation of the individual’s genetic makeup to his or her response to specific drugs, as an important part of therapeutic

PHARMACOEPIDEMIOLOGY

study of drugs effects at a population level

PHARMACOECONOMICS

branch of health economics

PHARMACOECONOMICS

quantify the cost and benefit of drugs used therapeutically

PHARMACOTOXICOLOGY

deals with the study of adverse effects of drugs

PHARMACOTOXICOLOGY

Mechanism of toxicity (MOT)

DRUGS

Are low MW chemical substances that interact with macromolecular targets in the body to produce effect

1. Functional Modifiers

2. Replenishers

3. Diagnostic Agents

4. Chemotherapeutic Agent

Classifications of drugs

Functional Modifiers

agents that modify/alter physiological or

biochemical activities of cells in the body

Replenishers

supplements/endogenous substances that are lacking or insufficient

Chemotherapeutic Agents

inhibit growth/kill cells that are considered foreign in the body