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Hyponatremia
Decrease serum sodium concentration <135 mmol/L
Hypovolemic hyponatremia
Low Na and water
Diuretics
Potassium depletion
Aldosterone deficiency
Ketonuria ( DM ) ( Low Na in DM due to polyuria )
Salt losing nephropathy ( ex. Polycystic kidney disease ( forms cyst, na+ is not absorbed: loss of)
Renal loss ( Na >20mmol/day)
Vomiting ( gastric juices are excreted , excessive acid loss causes increase bicarbonate )
2. Diarrhea
Excess fluid loss
Potassium depletion
Extra renal loss or cellular shift ( Na < 20 mmol/day)
Normovolemic hyponatremia
Normal volume