Chapter 8 Cirrus Review

Certain drugs should not be taken within two weeks prior to the initiation of an MAOI. This time interval is known as the

washout peroid

Which of the following medications must have blood levels drawn within 5 to 10 days after the start of therapy to ensure therapeutic doses are being given?

lithium

Cyclic antidepressants are sometimes used for which of the following side effects?

sedation

_____ is an antipsychotic drug that has a ceiling dose. Doses exceeding 800 mg can cause pigment deposits in the retina, sometimes leading to blindness.

Thioridazine

Given an example of an anxiety drug

buspirone

What is the term used to describe involuntary movements of the mouth, lips, and tongue that are sometimes accompanied by involuntary movements of the limbs or trunk?

**tardive dyskinesia**

If a patient is taking phenelzine, they should avoid all of the following *except*

fresh shellfish

All SSRI drugs are contraindicated with the use of which of the following drug classes?

MAIOs

Which of the following serotonin and norepinephrine reuptake inhibitor drugs is available for hot flashes, fibromyalgia, and neuropathic pain?

desvenlafaxine

three examples that are controlled substances used to treat insomnia

temazepam, eszopiclone, triazolam

Which of the following antidepressants is a dopamine and norepinephrine reuptake inhibitor with no direct effect on serotonin or monoamine oxidases?

bupropion

The serotonin and norepinephrine reuptake inhibitor Cymbalta, carries an indication for the treatment of both depression and

pain

Paliperidone uses an extended-release technology called *osmotic controlled-release oral delivery system*. What should patients be made aware of in regard to this technology?

ghost tablets in the stool

Which of the following psychiatric disorders is characterized by feelings of pessimism, worry, intense sadness, loss of concentration, slowing of mental processes, and problems with eating and sleeping?

depression

An overdose of TCAs may result in CNS toxicity and

**potentially fatal cardiac arrhythmias.**

Which of the following drugs is *not* a cyclic antidepressant?

trazodone

Which of the following drugs is an antipsychotic?

clozapine

An initial prescription of Zyban for smoking cessation should be dosed as

once daily for 3 days

Modafinil is a nonamphetamine, Schedule IV drug approved for which of the following conditions?

shift-work disorder

Which of the following drug classes have anticholinergic side effects, which may decrease urinary urgency?

TCA’s

Which of the following drugs is an anticholinergic drug that may produce an immediate, but not necessarily complete, response to excess muscle activity resulting from antipsychotic drug administration?

benztropine

Which of the following classifications of drugs inhibit the activity of the enzymes that break down catecholamines?

MAOI’S

Wellbutrin XL should be used with caution in patients with a history of which of the following conditions?

seizures

Zoloft and Zocor may be mistaken for one another. Zoloft is used to treat _____ and Zocor is used to treat elevated cholesterol levels.

depression

Which of the following drugs is used for depression, Parkinson's disease, and Alzheimer's disease and is available as a transdermal patch?

selegiline

Which herbal supplement should *not* be used with other antidepressants due to an increased risk of serotonin syndrome?

St. Johns Warts

The primary indication for using antipsychotic drugs is to treat which of the following conditions?

schizophrenia

The drug lorazepam used to treat anxiety is classified as a controlled substance schedule in which of the following schedules?

Schedule I

Which of the following drugs is classified as an SSRI?

Sertraline

The antidepressant _____ should be used with caution in patients taking over-the-counter ginkgo biloba due to the possibility of serious interactions.

trazadone

Which of the following is a serious side effect of clozapine drug therapy, making it necessary for the dispensing pharmacist to review blood levels?

reduction in white blood cells

Which of the following is a pure opiate antagonist that blocks the effects of endogenous opioids released as a result of alcohol consumption?

natrexone

Prozac and Proscar are "look-alike and sound-alike" medications and are, therefore prone to error. Prozac is used to treat _____ and Proscar is used to treat _____.

**depression; enlarged prostate**

Which of the following tricyclic antidepressants is available as a cream used to treat pruritus (itching) in adults and geriatric patients?

doxepin

Celexa is often confused with Cerebyx and Celebrex, therefore, caution must be used in dispensing. Celexa is used to treat _____, while Cerebyx is an anticonvulsant, and Celebrex is used to treat arthritis.

depression and OCD

What drug class is often used for the detoxification process for alcohol overdose?

benzodiazepines

What term is used to describe a mood of hyperactivity, extreme excitement, and excessive elation?

mania

Which of the following SSRIs is used to treat a severe form of premenstrual syndrome?

fluoxetine

Low doses of prochlorperazine are commonly used for

nausea and vomiting

Which two neurotransmitters are believed to be most involved with schizophrenia and the drugs used to treat this disorder?

dopamine and serotonin

Fluoxetine is an example of an antidepressant that appears to work through which of the following mechanisms?

**It inhibits the reuptake of serotonin in the brain.**

What is a common side effect from taking antipsychotic medications?

weight gain

Which of the following drugs used to treat insomnia is a melatonin receptor agonist?

ramelteon

All benzodiazepines belong to which of the following controlled substance schedules?

Schedule I

Which of the following atypical antipsychotic drugs is the active metabolite of risperidone?

paliperidone

_________ is a very versatile drug because it has multiple unique dosage forms, including a cream used for itching and an oral liquid formulation sometimes prescribed by dentists?

doxepin

A patient with narcolepsy may be prescribed a

stimulant

What class of drugs is considered to be the standard of care for alcohol (ethanol) detoxification?

benzodiazepines

Which of the following drugs is classified as a tricyclic antidepressant and has significant anticholinergic side effects?

imipramine

Which drug used to treat depression is also used for smoking cessation?

bupropion

A child with a bed-wetting problem might be prescribed a(n)

**tricyclic antidepressant.**

Which of the following newer antipsychotic drugs is classified today as being "atypical?"

**aripiprazole**

Which of the following serotonin and norepinephrine reuptake inhibitors is used to treat diabetic neuropathy?

**duloxetine**

Which of the following is a typical side effect in a patient is taking a therapeutic dose of lithium?

slight tremor of hands

All drugs in the SSRI class have a boxed warning for which of the following conditions?

**increased risk of suicide**

With which psychiatric disorder do patients suffer from alternating episodes of major depression and mild-to-severe agitation?

bipolar disorder

Why should patients avoid consuming alcohol while taking atypical antipsychotic medications?

**Excessive sedation and hallucinations can occur.**