Poxviridae, Adenoviridae, and Papillomaviridae

poxviridae virus

variola

poxviridae characteristics

• linear structure

• enveloped

• has its own DNA dependent RNA polymerase

  • so it doesn’t need host machinery in nucleus

• replicates in cytoplasm WEIRD

• largest of DNA viruses

variola causes this disease

smallpox

smallpox clinical features

• vesicular skin eruptions

• skin rashes similar to chickenpox with fever

what DNA virus is considered eradicated?

smallpox

smallpox can be used as a potential agent of _________

bioterrorism

smallpox prevention

because of its eradication, we no longer routinely vaccinate for smallpox

• military are given routine vaccination (risk of bioterrorism use)

adenovirus characteristics

• linear structure

• no envelope

number one cause of tonsilitis

adenovirus

adenovirus clinical features

infection of respiratory tract, GI tract, and eyes (REALLY BAD PINKEYE)

papillomaviridae virus

HPV - human papillomavirus

HPV characteristics

• circular structure

• no envelope

HPV causes —

warts - proliferative epithelial lesions

cervical cancer in women

most common STD

HPV

HPV in women is commonly—

asymptomatic

diagnosis of women with HPV

pap smear or molecular methods