Semisolid dosage forms and Sterile Dosage Form

Incorporation

Mix components to achieve a uniform preparation thru LEVIGATION or GEOMETRIC DILUTION

Fusion

Components are combined together thru MELTING TOGETHER (70-75 °C) and cooled with constant stirring until congealed

Ointment roller Mills, Unguator

Equipments for INCORPORATION

Stem-jacketed Kettle

Equipment for FUSION

Hand-rolling

Molding of suppository by using FINGERS

Compression

Uses a mold => Ice cube trays

HEPA (High Efficiency Particulate Air)

This is used to ensure cleanliness in clean areas

Clean areas

An area with defined environmental control of particulate and microbial contamination

Microns should be ≥ 0.5 micron in 1 cubic foot of samplexair

Airlock

An enclosed space with 2 or more doors