Minor blood group systems

Diego

DI: 010

Diego

2 sets of anti-thetical antigens (Dia, Dib/Wra, Wrb) and 3 low incidence antigens (Wda, delayed HTR and HDN Rba, WARR)

Dia/Dib

Wra, Wrb

Two sets of anti-thetical antigens

Wda, Rba, WARR

3 low incidence antigens

Dia antigen

useful tool in anthropological studies of Mongolian Ancestry

Dia and Dib

found in Anion exchange molecule (AE-1)

Anti-Dia and Anti-Dib

• RBC stimulated

• IgG

• Do not bind complement and reactive DAT

Chido/Rodgers

H/RG:011

Chido/Rodgers

Consist of 9 antigens

CH/RG antigens

Antigenic determinants of human complement C4 (C4a and C4b)

Anti-CH / RG abs

Can be neutralized by fresh human serum

Xg systems

XG:012

Xg systems

Only 1 antigen, and 2 resulting phenotypes Xga (+) Xga (-)

Xga allele

Loc on the short arm of X chromosome

Xga allele

More prevalent in women and associated with multiple transfusion

Anti Xga

Predominantly IgG

Reactive in IAT

Anti Xga

Binds complement but do not cause HDN and HTR

Xg system

Sensitive to enzymes

Bennett Goodspeed

Bg means

Bg systems

Related to human leukocyte antigens on RBC

HLA B7

Bga

HLA B17

Bgb

HLA A28

Bgc

Crom: 021

Cromer

Cromer

Associated with decay accelerating factor

DO: 014

Dombrock

Dombrock

Associated with ADP-ribosyl transferase 4

Gerbich

GE:020

Gerbich

Produced in glycoprotein C and D

IN: 023

Indian

Indian

Associated with CD 44

SC: 013

Scianna

Scianna

Assoc with erythroblast membrane associated protein

Cartwright

Found on the protein acetylcholinesterase

Anti Sd abs

Demonstrates characteristic shiny, refractile, mix-field agglutination