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Quaternary Ammonium Compounds (Quats)
Low-level disinfectant
Disrupt cell membranes
Used on surfaces (floors, furniture, bed rails)
Not effective vs spores, TB, non-enveloped viruses
Phenolics
Intermediate-level
Damage cell walls & proteins
Used on surfaces & non-critical equipment
Avoid in neonatal areas
Alcohol
Intermediate-level
Denatures proteins
Used on skin & small equipment
Fast acting, evaporates, not sporicidal
Halogens
Intermediate-level
Oxidize microbes
Used for water & surfaces
Broad activity, inactivated by organic matter
Glutaraldehyde
High-level disinfectant
Used for heat-sensitive devices (endoscopes)
Requires ventilation & monitoring
Ortho-phthalaldehyde (OPA)
High-level disinfectant
Used for endoscopes
Faster & less irritating than glutaraldehyde
Hydrogen Peroxide
Intermediate or high-level
Oxidizing agent
Used for surfaces & device sterilization
Environmentally friendly
Peracetic Acid
High-level / sterilant
Strong oxidizer
Used for instruments & endoscopes
Works even with organic matter
Chlorine
Intermediate-level
Used for blood spills & surfaces
Very effective but corrosive
Iodophors
Intermediate-level
Used for skin prep
Less irritating than iodine
Chlorhexidine
Low-intermediate
Used for skin & hand antiseptic
Long-lasting effect
Formaldehyde
High-level / sterilant
Used for preservation & sterilization
Toxic, potential carcinogen