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§Lymphatic system
Network of organs and vein-like vessels that recover fluid
•Inspect it for disease agents
•Activate immune responses
•Return fluid to the bloodstream
Lymphocytes
- (25% to 33%)
- increased numbers in diverse infections and immune responses
- Secrete antibodies and provide immune memory
FUNCTIONS of the respiratory system
1.Provides O2 and CO2 exchange between blood and air
2.Speech and other vocalizations
3. sense of smell
4. affects pH of body fluids by eliminating CO2
5. promote the flow of lymph and venous blood
surfaces of the lungs
costal, mediastinal, diaphragmatic
positions of the lungs
in the thorax, either side of the mediastinum.
position of the kidneys
retroperitoneal
T lymphocytes (T cells)
Lymphocyte that matures in the thymus and acts directly against antigens in cell-mediated immune responses.
B lymphocytes (B cells)
Lymphocyte that matures in the bone marrow and secretes antibodies.
Immune system definition
population that inhabits all organs and defends the body from agents of disease
nervous system
the body's speedy, electrochemical communication network, consisting of all the nerve cells of the peripheral and central nervous systems
what can Atelectasis result from
airway obstruction
Asthma
A chronic allergic disorder characterized by episodes of severe breathing difficulty, coughing, and wheezing.
Chronic bronchitis symptoms
§Symptoms include dyspnea (difficulty breathing), hypoxia (low O2 levels), cyanosis (poor circulation), and attacks of coughing
Chronic bronchitis
§Inflammation and hyperplasia of the bronchial tubes and an increase in bronchial mucosa
Squamous-cell carcinoma
most common form of lung cancer(Begins with transformation of bronchial epithelium into stratified squamous from ciliated pseudostratified epithelium)
Autoimmune diseases
failures of self-tolerance Immune system fails to distinguish self-antigens from foreign ones
Autoimmune diseases THEORIES
1.) Cross-reactivity
2. Abnormal exposure of self-antigens in the blood
3. Changes in structure of self-antigens
what are lymph nodes
gland-like structures found inside the lymphatic vessels
why do lymph nodes swell
the cells that circulate in the lymph are responsible for picking up cellular debris from the tissue
what does the phrenic nerve innervate
diaphragm
Five types of leukocytes
§Neutrophils
§Eosinophils
§Basophils
§Monocytes
- Lymphocytes
Eosinophils
(2-4%)- increased number in parasitic infections, Stand guard against parasites, allergens (allergy causing agents), and other pathogens
Neutrophils
(60% to 70%)
increased numbers in bacterial infections
Basophils
(<1%)
increased numbers in chickenpox, sinusitis, diabetes
Monocytes
(3%-8%)
increased numbers in viral infections and inflammation
Cross-reactivity for Autoimmune diseases is what
Some antibodies react against foreign antigens react to similar self-antigens THEY FORGET WHO IS ENEMY AND FRIEND
Abnormal exposure of self-antigens in the blood for autoimmune diseases is what
•Some of our native antigens are not exposed to blood so the body recognizes them as foreign- •Placental blood barrier
Changes in structure of self-antigens for autoimmune diseases is what
Viruses and drugs may change the structure of self-antigens
Acquired immunodeficiency syndrome (AIDS)
The most advanced, and fatal, stage of an HIV infection.
aids symptoms
§Early symptoms: flulike symptoms of chills and fever
- 200 cell count of T cells
- Person susceptible to opportunistic infections
- Candida (thrush)
- Kaposi sarcoma
question 18 is what
it is true
spirometry
the measurement of pulmonary function
Tidal volume is what
volume of air inhaled and exhaled in one cycle during quiet breathing (500 mL)
Inspiratory reserve volume define
§air in excess of tidal volume that can be inhaled with maximum effort (3000 mL)
Expiratory reserve volume define
air in excess of tidal volume that can be exhaled with maximum effort (1200 mL)
Residual volume define
air remaining in lungs after maximum expiration (1300 mL)
volume of air consumed during tidal volume
500 mL
volume of air consumed during inspiratory reserve volume
3000 mL
volume of air consumed during expiratory reserve volume
1200 mL
volume intake of air consumed for residual usage
1300 mL
the diaphragm is the prime muscle for what
breathing
secondary instrument for respiration is what
the intercoastals
where is the axillary
armpit
two types of Nephrons
cortical and juxtamedullary
what are cortical nephrons
§85% of all nephrons
§Short nephron loops
§Efferent arterioles branch into peritubular capillaries around PCT and DCT
what are Juxtamedullary nephrons
§15% of all nephrons
§Very long nephron loops, maintain salinity gradient in the medulla and helps conserve water
§Efferent arterioles branch into vasa recta around long nephron loop
specialized cells in glomerulus responsible for filtering plasma
podocytes
describe GFR too high
("diarrhea of urine filtration")
§Urine output rises
§Chance of dehydration and electrolyte depletion
describe GFR too low
("constipation of urine filtration")
§Wastes reabsorbed / Urine output decreases
§Azotemia (Excessive nitrogen, urea, waste in blood) may occur
what is azotemia
it is Excessive nitrogen, urea, waste in blood. it is in low GFR
what are kidney stones called
renal calculi
3 types of UTIs
cystitis, pyelonephritis, pyelitis
Cystitis
infection of the urinary bladder
Pyelitis
infection of the renal pelvis
Pyelonephritis
infection that reaches the cortex and the nephrons
process of respiration
ventilation, external respiration, internal respiration
first three parts of the larynx
Epiglottic cartilage (1):
Thyroid cartilage (2)
Cricoid cartilage (3):
Epiglottic cartilage
spoon-shaped supportive plate in epiglottis; most superior one
Thyroid cartilage
largest, laryngeal prominence (Adam's apple); shield-shaped
Cricoid cartilage
connects larynx to trachea, ringlike
three smaller paired cartilages of the larynx
- Arytenoid cartilages (4&5)
- Corniculate cartilages (6&7)
- Cuneiform cartilages (8&9)
Arytenoid cartilages (4&5)
posterior to thyroid cartilage
Corniculate cartilages (6&7)
attached to arytenoid cartilages like a pair of little horns
Cuneiform cartilages (8&9)
: support soft tissue between arytenoids and epiglottis
what supports the trachea?
C-shaped rings of hyaline cartilage
how are the lobar bronchi separated?
Three right lobar (secondary) bronchi & Two left lobar (secondary) bronchi
amount of Segmental (tertiary) bronchi
•10 on right, 8 on left
Pulmonary artery branches do what
closely follow the bronchial tree on their way to the alveoli
what are Bronchioles
smaller branches of the bronchi that are 1MM OR LESS IN DIAMETER
what are terminal bronchioles
The smallest conducting bronchioles- Measure 0.5 mm or less in diameter- •Have cilia that move mucus draining into them back by mucociliary escalator- gives off two or more smaller respiratory bronchioles
what are Respiratory bronchioles
microscopic branches that penetrate deep into lungs- Considered the beginning of the respiratory division- End in alveolar sacs
pneumothorax
presence of air in pleural cavity
Atelectasis
collapse of part or all of a lung
Apnea
temporary cessation of breathing
Eupnea ("Up-nea")
relaxed, quiet breathing
Dyspnea
labored, gasping breathing; shortness of breath
Hyperpnea
increased rate and depth of breathing in response to exercise, pain, or other conditions
hyperventilation
- increased pulmonary ventilation in excess of metabolic demand
Adenocarcinoma
§lung cancer that originates in mucous glands of lamina propria
Small-cell (oat cell) carcinoma
§Least common, most dangerous (TEST Q)
§Named for clusters of cells that resemble oat grains
§Originates in primary bronchi, invades mediastinum, metastasizes quickly to other organs
what is the largest lymph organ
the spleen
QUESTION: major site of lymph nodes is not where
the breast
Alveolar gas exchange
the back-and-forth traffic of O2 and CO2 across the respiratory membrane
where does incoming air stop
alveoli
Carbon monoxide (CO) does what
competes for the O2 binding sites on the hemoglobin molecule
what is carbon monoxide poisoning
carbon monoxide binds to hemoglobin blocking oxygen
Primary lymphatic organs ("brains")
§Red bone marrow and thymus
Secondary lymphatic organs ("brawn")
§Lymph nodes, tonsils, and spleen
the Thymus is apart of what system(s)
member of the endocrine, lymphatic, and immune systems
Polyuria
output in excess of 2 L/day
Oliguria
output of less than 500 mL/day
Anuria
0 to 100 mL/day
normal pee amount
about 2 liters
what do monocytes turn into
macrophages
Wandering macrophages
actively seeking pathogens
Fixed macrophages
phagocytize only pathogens that come to them
macrophages are what
§Very large, avidly phagocytic cells of the connective tissue
§Develop from monocytes
Leukocytes and Macrophages
Phagocytes that play a role in both nonspecific and adaptive
(specific) immunity.
ideal body temperature
98.6