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What is inheritance?
The transmission of genetic information from generation to generation
Where are chromosomes found?
In the nucleus of cells
What are chromosomes?
Thread like structures made of DNA carrying genes
What is a gene?
A short length of DNA that codes for a specific protein
What do genes control?
Characteristics by controlling protein production
What are alleles?
Different versions of the same gene
How many alleles does an individual have for each gene?
Two
Where do alleles come from?
One from the mother and one from the father
Define genotype
The combination of alleles an organism has
Define phenotype
The observable characteristics of an organism
What is a dominant allele?
An allele that shows with only one copy
What is a recessive allele?
An allele that only shows with two copies
Define homozygous
Having two identical alleles
Define heterozygous
Having two different alleles
What letters are used for alleles in genetic diagrams?
Capital for dominant lowercase for recessive
What determines sex in humans?
Sex chromosomes
What sex chromosomes do females have?
XX
What sex chromosomes do males have?
XY
Who determines the sex of the baby?
The father
Why does the father determine sex?
He provides X or Y sperm
What is protein synthesis?
The production of proteins from DNA instructions
What are the two stages of protein synthesis?
Transcription and translation
Where does transcription occur?
In the nucleus
What is transcription?
Copying DNA code into mRNA
Why can DNA not leave the nucleus?
It is too large
What is mRNA?
Messenger RNA that carries the code to ribosomes
Where does translation occur?
At ribosomes
What is translation?
Using mRNA to build amino acids into proteins
What is a triplet code?
Three bases coding for one amino acid
What controls amino acid sequence?
Base sequence of DNA
What is gene expression?
Whether a gene is switched on or off
Why are many genes switched off?
To save energy and resources
What are haploid cells?
Cells with one set of chromosomes
What are diploid cells?
Cells with two sets of chromosomes
How many chromosomes are in human body cells?
46
How many chromosomes are in human gametes?
23
What is mitosis?
Nuclear division producing identical cells
State three functions of mitosis
Growth repair asexual reproduction
Are cells produced by mitosis haploid or diploid?
Diploid
Are daughter cells genetically identical in mitosis?
Yes
What are stem cells?
Unspecialised cells that can divide and differentiate
What is the ultimate stem cell?
The zygote
What is meiosis?
Nuclear division producing genetically different cells
Why does meiosis occur?
To produce gametes
What type of cells does meiosis produce?
Haploid cells
How many cells are produced in meiosis?
Four
How many divisions occur in meiosis?
Two
Why does meiosis increase variation?
Recombination and random fertilisation
Give two differences between mitosis and meiosis
Mitosis produces identical cells meiosis produces variation
What is monohybrid inheritance?
Inheritance of one gene
What is a Punnett square?
A diagram showing possible allele combinations
What ratio is produced from heterozygous crosses?
3 to 1
What is codominance?
Both alleles affect the phenotype
Give an example of codominance
Blood groups
What alleles control blood groups?
IA IB and IO
Which alleles are codominant?
IA and IB
What is a sex linked characteristic?
A trait controlled by a gene on the X chromosome
Why are males more affected by sex linked disorders?
They have only one X chromosome
What is a carrier?
A female with one recessive allele
Give two examples of sex linked disorders
Haemophilia colour blindness
What is biotechnology?
Using organisms to make useful products
Why are bacteria useful in biotechnology?
They reproduce rapidly and make complex molecules
What are plasmids?
Small circular DNA in bacteria
Why are plasmids useful?
They transfer genes easily
What is fermentation?
Anaerobic respiration by microorganisms
What does yeast produce during fermentation?
Ethanol and carbon dioxide
How is yeast used in bread making?
Carbon dioxide makes dough rise
How is yeast used in biofuel production?
Ethanol is used as fuel
What enzyme is used in fruit juice production?
Pectinase
What does pectinase do?
Breaks down pectin in cell walls
Why do biological detergents contain enzymes?
To break down stains
Give two advantages of biological detergents
Lower temperatures and faster cleaning
What is lactose?
Sugar found in milk
What enzyme digests lactose?
Lactase
How is lactose free milk produced?
Adding lactase enzyme
What is penicillin?
An antibiotic
Who discovered penicillin?
Alexander Fleming
What produces penicillin?
Penicillium mould
What is an industrial fermenter?
A vessel for growing microorganisms
Why are fermenters kept aseptic?
To prevent contamination
Why is temperature controlled in fermenters?
To maintain optimum enzyme activity
What is genetic modification?
Changing genetic material by inserting genes
What is a transgenic organism?
An organism with genes from another species
What is recombinant DNA?
DNA containing genes from different organisms
Give an example of GM bacteria
Insulin producing bacteria
What enzyme cuts DNA?
Restriction enzymes
What enzyme joins DNA?
DNA ligase
Why are bacteria used for genetic engineering?
They share the same genetic code
What is a GM crop?
A crop with altered genes
Give one advantage of GM crops
Increased yield or pest resistance
What is the main source of energy for ecosystems?
The Sun
How does energy enter food chains?
Photosynthesis
What is a food chain?
A sequence showing energy transfer
What do arrows in food chains represent?
Energy transfer
What is a producer?
An organism that makes its own food
What is a consumer?
An organism that eats others
What is a food web?
Interconnected food chains
What does interdependence mean?
Species depend on each other
What is a pyramid of numbers?
Diagram showing number of organisms
Why can pyramids of numbers be inverted?
Large producers support many consumers