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208 Terms
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gene expression
The process of turning on a gene to produce RNA and protein, leads to speciation
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why gene expression is necessary
if there is no gene expression, will make every gene (protein) all the time, using lots of resources + space
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transcription (DNA to RNA)
where most gene regulation occurs in prokaryotes
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simultaneously
when does transcription and translation happen in prokaryotic cells
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repressors
proteins that suppress transcription of a gene in response to an external stimulus
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activators
proteins that increase the transcription of a gene in response to an external stimulus, multiple of these= enhancers
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inducers
small molecules that either activate or repress transcription depending on the needs of the cell and the availability of substrate
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operons
Proteins that are needed for a specific function are encoded together in blocks
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Jacob and Monod
the first to show the organization of bacterial genes into operons through the lac operon
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transcription factors
proteins encoded by regulatory genes
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RNA polymerase
makes mRNA strand
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operator
regulatory region located between the RNA polymerase binding site of the promoter and the transcriptional start site of the first structural gene
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sequence of an operon
promoter, operator, structural genes (in that order)
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the 3 regulators
activator, repressor, inducer
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constitutively expressed
Gene products that are needed consistently are ________ in prokaryotes.
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enhancers
regions that help increase or enhance the transcription of a distant gene, made up of activators
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splicing
when original DNA or RNA sequence is split up to only leave what needs to be turned into a protein
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exons
The regions of DNA or RNA that code for protein
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introns
a segment that doesn’t code for a protein + interrupts sequence
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miRNA (microRNA)
short single-stranded RNA molecules that are only 21–24 nucleotides in length. Like transcription factors and RBPs, mature miRNAs recognize a specific sequence and bind to the RNA to degrade the target mRNA. They rapidly destroy the RNA molecule.
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poly-A tail
long chain of adenine nucleotides added to mRNA to increase stability
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5’ cap
placed on 5’ end of mRNA to keep it from degrading when attached to poly-A tail (mRNA)
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3’ cap
placed on 3’ end of poly-A tail to keep from degrading when attached to mRNA (POLY-A TAIL)
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5’ end
phosphate
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3’ end
sugar
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RNA stability
the rate an RNA molecule decays at, it’s lifespan
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nuclear pore complex
holes in the nucleus that mRNA can come out of
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RNA splicing, RNA shuttling, RNA stability
the 3 versions of post-transcriptional control, if only one of these is not completed a protein can’t be synthesized
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histones
the proteins DNA wraps around to make chromatin
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nucleosome
DNA wrapped around a histone to control what parts of DNA can be accessed by proteins.
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epigenetic regulation
regulation due to histones making DNA accessible or inaccessible in eukaryotes
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sympatric speciation
when speciation happens even though they are not geographically seperated
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allopatric speciation
speciation caused by a geographical barrier
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promoter
where RNA polymerase and the transcription factors bind
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DNA bending protein
brings an enhancer into contact with transcription factors so it can increase transcription
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pea plant
Pisum Sativum, what Mendel used
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trait
a variation in the physical appearance of a heritable characteristic
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law of segregation
each gamete only gets one copy of a gene
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blending theory of inheritance
What Lamarck believed (the giraffe guy)
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continuous variation
like polygenic traits, have a continuous number of phenotypes
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discontinuous variation
monohybrid traits, dihybrid traits, non-polygenic traits; limited number of phenotypes
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model system
models that represent biological circumstances to run experiments on
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incomplete dominance
traits mix, neither is completely expressed
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codominance
spots, both traits are present
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autosomes
non-sex chromosomes
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hemizygous
when you only have 1 copy of a chromosome (males are hemizygous for x chromosomes)
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wild type
the most common geno/phenotype found in the wild, usually abbreviated with a +
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variants
any other geno/phenotype that is not most commonly found in the wild (like albinism)
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pleiotropic gene
a gene that affects multiple characteristics. inherited like single trait alleles
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multifactorial characteristics
Characteristics that are influenced by environmental as well as genes
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H.M.S Beagle
the ship Darwin traveled the world on
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convergent evolution
what makes vestigial structures, two organisms with similar traits but evolved seperately
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human economic pressures
One of the foundational concepts of natural selection was an essay on ________.
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divergent evolution
2 species that evolved similar traits due to a common ancestor
The field of biology that studies allele frequencies in populations and how they change over time
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adaptive evolution
increasing the frequency of beneficial traits
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frequency-dependent selection
there are 3 different lizards. Like a game of rock-paper-scissors, orange beats blue, blue beats yellow, and yellow beats orange in the competition for females. THE FREQUENCY OF ONE TRAIT IS DEPENDENT ON ANOTHER.
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sexual dimorphisms
differences between males and females of a species
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handicap principle
some sexual adaptations can put members of species at risk. (like a bright tail) this is the idea that the more risk, the more fit an individual is, since they can handle that risk
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good genes hypothesis
the idea that males have ornamental sexual traits because it corresponds with better genes
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honest signal
the idea that ornamental sexual traits on males mean they are actually superior and are not a “trick”
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perfect organism
natural selection will never create a ______.
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bottleneck effect
type of genetic drift where lots of alleles are taken out by a catastrophic event
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founder effect
type of genetic drift where a small group separates and creates own population with their set of alleles
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gene flow
flow of alleles in and out of a population due to migration
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phylogeny
the evolutionary history and relationship of an organism or group of organisms
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phylogenetic tree
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taxonomy
domain, kingdom, phylum, class, order, family, genus, species
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binomial nomenclature
the two-word scientific name of a species. ex: *Canis lupus*
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taxon
the names of each level of taxonomy (domain, kingdom, etc)