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mineralocorticoids
aldosterone
glucocorticoids
cortisol
glucocorticoids
cortisone
glucocorticoids
11-deoxycortisol
sex steroids
androgens: testosterone
sex steroids
estrogens: estradiol, estriol, estrone
sex steroids
progesterone
estrone (E1)
most abundant in post-menopausal women
estradiol (E2)
most potent
estradiol (E2)
most abundant in pre-menopausal women
estriol (E3)
metabolite of estradiol
estriol (E3)
major estrogen secreted in placenta
albumin
non-specific, carries many steroids
cortisol-binding globulin
cortisol and derivatives
cortisol-binding globulin
progesterone
sex hormone-binding globulin
testosterone
sex hormone-binding globulin
estradiol
primary hyperaldosteronism
aka Conn’s disease
secondary hyperaldosteronism
aka Waterhouse Friderichsen Syndrome
Waterhouse Friderichsen Syndrome
bleeding in the adrenal gland with meningococcemia caused by and organism
Neisseria meningitidis
organism that caused meningococcemia?
hypercortisolism
aka Cushing’s syndrome
Addison’s disease
most common in adrenal insufficiency
pheochromocytoma
a tumor in the adrenal gland
adrenalectomy
treatment for pheochromocytoma
Zimmerman reaction
measurement of 17-ketosteroids
Zimmerman reaction
purple color
Zimmerman reaction
520nm
Porter-Silber assay
for urine cortisol and derivatives
Porter-Silber assay
yellow derivative
Porter-Silber assay
410nm
Kober reaction
for urine estrogen determination
Kober reaction
reddish-brown color
Kober reaction
472nm
Kober reaction
512nm
Kober reaction
556nm