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Respiratory System with Dr. Pernici @ LaTech
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what does the respiratory system consist of?
passages that filter, moisten, and warm incoming air and transport it into the body, lungs, and the many microscopic air sacs where gases are exchanged
what does the respiratory system do other than circulate oxygen?
produced vocal sounds, helps with sense of smell, and helps regulate blood pH
respiration
process of exchanging gases between the atmosphere and body cells
external respiration
ventilation / breathing; allows gas exchange in the lungs
internal respiration
gas transport in blood and exchange with body cells
cellular respiration
process of ATP production in mitochondria, which uses oxygen to harness energy and gives off carbon dioxide
what events does respiration consist of?
external, internal, and cellular respiration
what subdivisions can the organs of the respiratory system be divided into?
the upper and lower respiratory tracts
what organs are included in the upper respiratory tract?
nose, nasal cavity, sinuses, pharynx, larynx
what organs are included in the lower respiratory tract?
trachea, bronchial tree, lungs
describe the structure of the nose.
covered with skin and supported by muscle, bone, and cartilage. two nostrils which allow air to enter and leave nasal cavity. has internal hairs that prevent large particles from entering
nasal septum
divides the nasal cavity into left and right portions
nasal conchae (turbinate bones)
structures in the nasal cavity that curl in from the lateral walls, forming passageways called meatuses
meatuses
passageways created from nasal conchae
where are olfactory receptors located?
in the upper portion of the nasal cavity
what lines the nasal cavity?
pseudostratified ciliated epithelium / mucous membrane
what is embedded in the pseudostratified ciliated epithelium of the nasal cavity?
goblet cells
what do goblet cells secrete?
mucus
what is the purpose of nasal mucus?
traps dust and pathogens. warms, moistens, and filters incoming air
what is the purpose of the cilia in the nasal cavity?
they sweep the mucus toward the pharynx, where it is swallowed
sinuses
air-filled spaces in the maxillary, frontal, ethmoid, and sphenoid bones of the skull
name the sinuses of the skull
maxillary, frontal, ethmoid, sphenoid
what is the purpose of sinuses?
resonate voice and reduce the weight of the skull
sinusitis
causes sinus pressure and headache. may result in blockage of sinus drainage from allergic reaction
what does smoking do to cilia?
slows and eventually paralyzes them
smoker’s cough
cilia no longer function, excess mucus is produced, and mucus must be coughed up
what does smoker’s cough lead to?
chronic bronchitis
chronic bronchitis
bronchial thickening, resulting in difficulty with expiration
pharynx
passageway for food from oral cavity to the esophagus and passageway for air between the nasal cavity and larynx. aids in producing sound for speech
what is the pharynx divided into?
nasopharynx, oropharynx, laryngopharynx
what is the difference between ventilation and respiration?
respiration is the exchanging of gases between the atmosphere and bodily cells, while ventilation is the breathing of air in and out of the body
what types of cartilage is included in the larynx?
thyroid, cricoid, epiglottic, arytenoid & corniculate, cuneiform
what part of the larynx is formed by thyroid cartilage?
adam’s apple
thyroid cartilage of the larynx
shieldlike structure
cricoid cartilage of the larynx
marks the lowermost portion of the larynx
epiglottic cartilage of the larynx
central part of the epiglottis, keeps food and liquid from entering air passages
arytenoid & corniculate cartilage of the larynx
attachments for muscles regulating tension on vocal cords and close larynx during swallowing
cuneiform cartilage of the larynx
between epiglottic and the arytenoid, stiffens soft tissues
true vocal cords
lower folds of the larynx that produced vocal sounds by forcing air between the folds, vibrating them
false vocal cords
upper (vestibular) folds that do not produce vocal sound. they protect the airway and help it close during swallowing
the larynx contains ___ pairs of horizontal ___________ composed of muscle and connective tissue
2, vocal folds
what is pitch of voice controlled by?
contracting/relaxing laryngeal muscles, changing the tension
what is intensity of voice controlled by?
the force of air passing over vocal cords
glottis
the true vocal cords and the opening between them
vocal cords are ______________ during normal breathing
relaxed
epiglottis
small, flexible cartilage flap in front of the larynx & vocal cords that closes over the windpipe when swallowing
what lines the trachea?
ciliated mucous membrane and goblet cells
what does a blocked trachea lead to
asphyxiation
tracheotomy
a procedure that cuts an opening in the trachea to insert a tube for air exchange. done, for example, if an object is lodged in the larynx or trachea
list all the branches of the bronchial tree.
right/left main (primary bronchi, lobar (secondary) bronchi, segmental (tertiary bronchi), intralobular bronchioles, terminal bronchioles, respiratory bronchioles, alveolar ducts, alveolar sacs, alveoli
right and left main (primary) bronchi
branch from the trachea, each leading to a lung
lobar (secondary) bronchi
branch from the main bronchi. 2 on the left, 3 on the right
segmental (tertiary) bronchi
each enters a segment. 8 on the left, 10 on the right
intralobular bronchioles
each enters a lobule
how many terminal bronchioles are in each lobule?
40-80
respiratory bronchioles
first structures to conduct gas exchange, alveoli bud from the sides of their walls
alveolar ducts
branches of respiratory bronchioles
alveolar sacs
outpouchings of alveolar ducts
alveoli
microscopic air sacs that perform gas exchange. open into sacs
what does the main bronchi have instead of C-shaped rings?
cartilaginous plates
describe the structure of respiratory tubes.
main bronchi branch from the trachea. as they continue to branch, they become narrower, decreasing the amount of cartilage. the cartilage eventually disappears when we reach the bronchioles, which allows changes in diameter of the bronchioles. smooth muscle becomes prominent, but eventually diminishes from bronchioles to alveolar ducts, where it disappears. as the respiratory tubes become thinner, epithelium changes.
what type of epithelium is in larger tubes of the respiratory system?
pseudostratified ciliated columnar epithelium
what type of epithelium is in respiratory bronchioles?
simple cuboidal epithelium
what type of epithelium is in alveoli?
simple squamous epithelium
what is bronchodilation and bronchoconstriction?
changes in diameter of the bronchioles
describe how alveoli work.
O2 diffuses through alveolar, then capillary walls to enter the blood. CO2 then diffuses from the blood to the alveoli
TRUE OR FALSE: branches of the respiratory system perform gas exchange.
false
ventilation
movement from air from outside of the body into the bronchial tree and alveoli
inspiration
inhalation
expiration
exhalation
what does one respiratory cycle consist of?
one inspiration + the following expiration
what moves air into the lungs?
atmospheric pressure
what is the role of atmospheric pressure upon inspiration?
forces air into the lungs
when are atmospheric and alveolar pressure equal?
when respiratory muscles are at rest
Boyle’s Law
pressure and volume of gases are inversely proportional
what is the role of intra-alveolar pressure in inspiration?
once pressure inside the alveoli decreases, atmospheric pressure pushes air into the airways
during normal, resting inspiration, how do the diaphragm and intercostal muscles move?
to enlarge the size of the thoracic cavity
what is the role of surfactant in inspiration?
reduces surface tension in the alveoli, aiding in lung expansion
what is the role of surface tension in the pleural cavity?
aids in lung expansion
what muscles expand the lungs during normal, resting inspiration?
diaphragm and external intercostal muscles
what muscles expand the lungs during maximal, deep inspiration?
diaphragm and external intercostal muscles IN ADDITION TO pectoralis minors, sternocleidomastoids, scalenes
does expiration require the contraction of muscles?
normal, resting: no
maximal, forced: yes
how does normal, resting expiration occur?
elastic recoil of the lung tissues and abdominal organs occurs, returning tissues to their original shape ad expelling air. surface tension develops on the moist surfaces of the alveolar linings, shrinking alveoli
how do thoracic and abdominal wall muscles aid in expiration?
when contracted, internal intercostal and abdominal muscles create pressure that forces the diaphragm into a higher position, pushing more air out of the lungs during maximal, forced expiration
tidal volume
amount of air entering/leaving during the respiratory cycle (500 mL)
inspiratory reserve volume
amount of air + tidal volume entering lungs during forced maximal inspiration (3000 mL)
expiratory reserve volume
amount of air + tidal volume leaving lungs during maximal expiration (1100 mL)
residual volume
amount of air in the lungs after forceful expiration (1200 mL)
vital capacity
inspiratory reserve volume + tidal volume + expiratory reserve volume
inspiratory capacity
tidal volume + inspiratory reserve volume
functional residual volume
expiratory reserve volume + residual volume
total lung capacity
vital capacity + residual volume
anatomic dead space
amount of air not reaching alveoli
minute alveolar ventilation
amount of new atmospheric air moved into respiratory passages each minute (tidal volume x breathing rate)
alveolar ventilation rate
volume of new air reaching alveoli and is available for gas exchange (tidal volume - dead space x breathing rate)
coughing mechanism
deep breath taken, glottis closes. air forced against glottis, opening it and blasting air upwards
sneezing mechanism
deep breath taken, glottis closes. air forced against glottis, opening it and blasting air upwards. air is directed into the nasal cavity by depressing the uvula
laughing mechanism
deep breath released in a series of short expirations
crying mechanism
deep breath released in a series of short expirations
hiccupping mechanism
diaphragm contracts spasmodically while glottis is closed