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circulatory system
the organs and tissues involved in circulating blood and lymph through the body
what are the two chambers of the heart
upper chambre(atria) and lower chambre(ventricles)
circulatory system process
-deoxygenated blood enters right atrium via vena cava
-blood moves to right ventricle and the pumped to pulmonary artery
-pulmonary artery carries deoxygenated blood to lungs where it becomes oxygenated
-oxygenated blood exits lungs via pulmonary vein
-blood enters left atrium
-then left ventricle
-blood is pumped into aorta where oxygenated blood is carried to body
features of transport systems
vessels that carry materials from one part of the organism to another
how is oxygen transported into blood
from lungs to all bodys cells
how is carbon dioxide transported into blood
from all bodys cells to lungs
how is glucose transported into blood
from digestive system to liver the all body cells
how is urea transported into blood
from liver cells to kidneys
heart
muscular organ
What does heart pump
blood
what is blood
bodily fluid
What two circuits does the heart pump blood into?
pulmonary circuit and systemic circuit
pulmonary circuit
carries blood to the lungs for gas exchange and returns it to the heart
systematic circuit
carries blood between the heart and the rest of the body
what must be open for blood to flow
valves
faulty heart valve
Heart valve that doesn't open properly restricting flow or leaks into atrium
faulty heart valve replacement
biological valve from donor
mechanical valve made from durable materials
specialised cells in right atrium
generate electrical signals that make heart contract
artificial pacemakers
Electrical devices used to correct irregularities in the heart rate
blood vessels
arteries, veins, capillaries
arteries
carry blood away from the heart
What type of blood do arteries typically carry?
Oxygenated blood, except for pulmonary arteries
What are the characteristics of the walls of arteries?
Thick, muscular, and elastic
What is the lumen size of arteries?
Narrow
Under what pressure do arteries carry blood?
High pressure
veins
carry blood to the heart
What type of blood do veins typically carry?
deoxygenated blood except pulmonary vein
What are the characteristics of the walls of veins?
thin walls and less muscular tissue than arteries
What is the lumen size of veins?
large
Under what pressure do veins carry blood?
low pressure
capillaries
Smallest blood vessels
walls of capillaries
only one cell layer thick to allow for exchanges between blood and tissue
composition of blood
plasma, red blood cells, white blood cells, platelets
plasma function
transporting co2 to lungs
digested molecules from small intestine
waste products to kidneys
red blood cells function
transport oxygen
white blood cells function
fight infection and disease
platelets function
blood clotting
red blood cells adaptations
-contain haemoglobin
-biconcave shape to max surface area
-no nucleus or mitochondria
-thin
What are the different types of white blood cells
Phagocytes
Lymphocytes
Phagocytes
They engulf and destroy unwanted microorganisms that enter the blood via the process phagocytosis
They are part of the immune system
Lymphocytes
Produce antibodies when a foreign body such as microorganisms enter the body
Part of immune system
How do platelets stop bleeding
-they have proteins on their surface which enables them to stick to breaks in blood vessels and clump together
-they secrete proteins that result in a series of chemical reactions that make blood clots which plugs a wound
Where are blood products produced from
Blood from Blood donors
Why are blood products screened
-for infectious agents such as HIV
-for their blood group
-for the presence of certain antibodies
Coronary heart disease
When the coronary arteries become blocked by fatty build up of material caused by bad cholesterol
What do coronary arteries store
Blood
what consequence does blocked arteries have on a person
-oxygen reaching the heart muscle is reduced
-chest pain if left untreated
-heart attack may occur and cause damage or even death
What are the two ways of treating coronary heart disease
Stents and statins
Statins
A drug that help lower cholesterol in blood
They do this by lowering its production in the liver
Disadvantages to statins
-side effects such as headaches
-long-term medication
-not suitable for everyone I.e pregnant women
Stents
When a catheter is inserted into arteries
The balloon is inflated to widen arteries
Catheter is removed
How do stents help
Widen the narrow arteries to restore and maintain blood flow
Advantages to stents
-long term solution
-for those who found drugs didn’t work
-made of metal alloy so doesn’t lead to immune response in patient
Risk of stent
Risk of bleeding , heart attack or stroke during operation
two sources of replacement heart valves
mechanical
biological
Heart transplant
Required in cases of heart failure where heart fails to pump sufficient blood and organs are starved of oxygen
Limits of heart transplant
Limited amount of donors in UK and carried out by small amount of hospitals
Risk of rejection by body’s immune system
artificial hearts
Plastic devices used occasionally whilst patients are waiting for heart transplant
Disadvantages of artificial transplant
May wear out
Blood clots may stick to mechanical valve
What is pulse measured in
Beats per minute
What scanning technique can be used to measure blood flow
MRI scan