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130 Terms
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Chromosomes
Humans have 46 \____in their somatic cells
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Autosomes
First 22 PAIRS of chromosomes
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Sex Chromosome
Last pair of chromosomes
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Male
XY
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Female
XX
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The Cell Cycle
Period of time from the beginning of one cell division to the beginning of the next
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M Phase (mitosis)
The division of the cell nucleus and cytokinesis
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G1 phase
Intense growth and activity
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S Phase
Copying of chromosomes
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G2 Phase
Intense growth and activity and organelles and proteins required for cell division are produced
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Mitosis-Asexual Reproduction
Produces somatic cells
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Prophase
1st phase of mitosis where chromosome become visible and centrioles separate and take up positions on opposite sides of the nucleus;Nucleolus disappears;nuclear envelope breaks down
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Metaphase
2nd phase in Mitosis where chromosomes line up in the middle of the cell and Microtubules connect the centromere of each chromosome to the poles of the spindle
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Telophase
4th phase in mitosis where chromosomes become loose and begin to disperse, nuclear envelope reforms, spindle breaks apart, a Nucleolus reappears, and cytokinesis
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Anaphase
3rd phase of mitosis where centromeres split, chromatids separate and become individual chromosomes, chromatids get pulled apart to the pole of the spindle, and ends when they stop moving
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Meiosis- Sexual Reproduction
Produces gametes
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Meiosis
A process of reduction division in which the number of chromosomes per cell is cut in half
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Homologous
Two sets of chromosomes
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Meiosis I
Chromosomes line-up similar to mitosis, except the homologous chromosomes for a tetrad and occurs during prophase I and 2 new cells are formed
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Nondisjunction
Failure of homologous chromosomes to separate during meiosis
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Meiosis II
Cells from meiosis I enter but don't undergo chromosome replication and anaphase II occurs
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Spermatogenesis
Occurs in males to produce sperm; animals\=testes; flowers\=anther(stamen); produces haploid cells to fuse with an egg to form a zygote
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Oogenesis
Occurs in females to produce eggs; animals\=ovary; flowers\= ovary(pistil); produces haploid cells to fuse with a sperm to form a zygote; only 1/4 of the haploid cells become the ovum
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The Central Dogma
DNA-\>RNA-\>Protein
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DNA
A molecule that carries genetic information which determines which proteins to make
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Nucleotides are made of...
5 carbon sugar, a phosphate group, and a nitrogen base
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Adenine pairs with...
Thymine
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Guanine pairs with...
Cytosine
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DNA Replication
Copying DNA ensuring that each resulting cell will have a complete set of DNA molecule
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Differences between DNA and RNA
Deoxyribose-\>Ribose
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Thymine-\> Uracil
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Double Helix-\>Single Stranded
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RNA
The intermediate between DNA and a protein
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Transcription
The process of making RNA from DNA and happens in the nucleus of eukaryotes but in the cytoplasm of prokaryotes
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RNA Polymerase
Scans the genome for the promoter region of DNA
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Exons
Expressed message
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Introns
In-between message that gets cut out of the mRNA to make the mature transcript
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Alternative Splicing
Allows to mix-n-match exons to make different proteins from the same sequence
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Translation
Matching an amino acid to the mRNA in order to make the protein code
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AUG
Start signal
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UAG,UAA,UGA
Stop signals
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Mutation
A change in DNA sequence
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Mutations in the DNA or RNA sequence produce...
The wrong amino acid sequence
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Point Mutations
Change one or two base pairs
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Frameshift Mutations
Change in the codon reading frame
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Silent Mutation
The mutation goes unnoticed; doesn't change the sequence
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Missense
An insertion, deletion, or substitution that would make the message different
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Nonsense
Really bad; a stop codon is created and the message stops prematurely
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Selective Breeding
Allowing only those animals with desired characteristics to produce the next generation
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Genetic Engineering
Making changes in the DNA code of living organisms
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Restriction Enzymes
Cuts DNA at a specific sequence of nucleotides
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Recombinant DNA
Taking DNA and "pasting" it to another organism's DNA