Module 4- Psychopharmacology

Which is the correct order for the life cycle of a drug molecule?

absorption>distribution>metabolism>excretion

If a drug is injected into the space beneath the skin, it is a:

subcutaneous injection

A steroid cream is an example of

topical administration

On a dose-response curve, what do we call the point at which increases in the dose of a drug do not produce stronger effects?

Point of maximum effect

in terms of determining the safety of a therapeutic drug, which is better?

a large margin of safety

(Blank) is a decrease in the effectiveness of a drug that is administered repeatedly

tolerance

A drug that inhibits the effects of a specific neurotransmitter on the postsynaptic cells is an (antagonist) drug

antagonist

L-DOPA is a drugs used to treat Parkinson’s disease that can have an agnostic effect. It can act as a (blank), helping the brain to synthesise the neurotransmitters dopamine

precursor

If a drug is stopping neurotransmitter from being stored in a synaptic vesicle, it is having a (blank) effect

antagonistic

If a drug binds to the same binding site a neurotransmitter normally attaches to, then it is having a (n) (blank) effect

direct

Which amino acid neurotransmitter has an excitatory effect?

glutamate

Which amino acid neurotransmitter has an inhibitory effect?

GABA

if glutamate is not removed from a synaptic cleft gluatamate

excitotoxcity

Which neurotransmitter is involved in muscle contraction in the PNS?

acetylcholine

Which monoamine neurotransmitter can result in both EPSPs and IPSPs and is most associated with attention, learning and the reinforcing effects of drugs?

dopamine

which neurotransmitter is most closely associated with vigilance and the locus coeruleus of the dorsal pons?

norepinephrine

The neurotransmitter that is a direct precursor for norepinephrine is

dopamine

SSRIs (blank) the reuptake of serotonin from the synaptic cleft

inhibit

Peptides are released from

all parts of the terminal button

Anandamide is a type of (blank) neurotransmitter

endocannabinoid