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Sterile compounding
preparation and mixing of a medication in an environment free from bacteria, viruses, or any other potentially infection organisms
What USP is followed in aseptic technique
USP 797
Examples of CSP’s prepared in a hospital pharmacy
Large volume and small volumer parenteral, hazardous drugs, and intrathecal prepataions(medications that go into the spine)
Stock room
where all the supplies for sterile compounding
What is in the stock room
medications, SWI, needles, syringes, tubing, IV fluids, and other supplies need to prepare a CSP
Ante room
place where you don and doff PPE, scrub, perform claculations, and gather supplies
What is prohibited in the Ante Room
CARDBOARD BOXES
Clean room/buffer area
where you actually PREPARE your CSP
The buffer area has an iso class of
7
The PEC has an iso class of
5
Where do you prepare the sterile product
6 inches inside the PEC hood
What is a PEC
Primary Engineering Control, which is a device or room that creates a controlled environment for compounding medications. PECs are also known as hoods.
Two types of PECs
Horizontal and Vertical
What is required for sterile compounding
sterile syringe
What are critical sites on the syringe
inner plunger shaft and needle hub
Nosocomial infection
an infection that develops while a patient is in the hospital or receiving medical care
If there was a nosocomial infection outbreak who would investigate
ICC
What is the similarity between a compounding aseptic isolator and horizontal hood?
both vent air through a high-efficiency particulate air (HEPA) filter ventilation system
“Spiking“ is what?
common term used by nurses when they have to pierce an IV bag
Where are the PECs located
the clean room/buffer area
Clean room airflow
airflow is always blowing out of the high positive pressure in this area
When should the prefilters in a PEC be changes
according to the manufacturers instructions
PPE order
Shoe cover, hair cover, face mask, hand wash, and gloves
When preparing an ampule
a filtered needle must be used in addition to a regular needle
Filter needles
is only for ONE DIRECTIONAL use only
How often will your aseptic practices be tested
6 monhsw
what is sterility testing
checking if your aseptic practices are good and if you fail you could lose your job
What drugs need to be protected from light
Doxycycline and Amphotericin B
What will a nurse use to administer insulin
10-drop set
When is a 24 hour supply stocked
each morning
STAT orders should be prepared immediately ___
usually within 15 minutes or less
Can you return unit doose medications?
yes, as long as the package is unopened
ADMS
automated dispensing system
Benefits of ADMS
organized work flow, invnetory management, and keeps medication secure
Purpose of eMAR tech(electronic medication administration record)
to keep track of medication administration (helps staff communicate and know when a patient has received medication)
Benefits of Electronic health records
they allow interoperability with in the hospital setting
Class I drug recall
most serious. Death or irreversible damage
Class II drug recall
The drug may cause temporary or reversible health effects, but serious harm is unlikely.
Class III drug recall
The drug is unlikely to cause harm but violates FDA regulations (e.g., packaging issues, minor defects)
Class IV drug recall
known as a "notification" or "market withdrawal", is for situations where a drug does not violate FDA regulations but has a known, minor default, and no threat to patient
Sentinel event
someone has been seriously injured or has died
FDA reporting systems
MedWatch, MEdication Error Reporting System (MERP)
Importatn thing to remember regarding penicillin countring
ALWAYS wipe the counting tray with alcohol just in case the next patient is allergic to this drug
Medication error
a preventable event that may cause of lead to inappropriate medication use or patient hardm
Nuclear medicine
involves the preparation of radioactive pharmaceuticals (agents used to diagnose certain medical problems or treat certain diseases)
Prescription error
Mistake in writing the prescription (e.g., wrong drug, incorrect dose, or unclear instructions).
Omission Error
Failing to give a prescribed dose of medication.
Wrong time error
Giving medication at the incorrect time (outside the allowed time frame).
Unauthorized error
Giving a drug not authorized for the patient (wrong prescription or order).
Improper dose error
Giving too much, too little, or an unapproved dose.
Administration error
Mistake in how the drug is given (wrong route, technique, or preparation)
Wrong drug error
Giving the incorrect medication (mix-up in selection or dispensing).
Wrong patient error
Giving the medication to the wrong person (due to ID confusion).
Comission error
Documenting or carrying out a medication order incorrectly.
Distraction error
Errors caused by interruptions or multitasking.
Harmful effects of hazardous drugs
teratogenicity, genotoxicity, and organ toxicity
Where are hazardous drugs prepared
Vertical PEC aka. biological safety cabinet
When receiving inventory for chemo drugs ___
always wear gloves to check the order in
Who are most hospitals accredited by
The Joint Commission (TJC)