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What is the primary target of antibiotics?
Viruses
Parasites
Bacteria
Fungi
Bacteria
How do antibiotics hinder bacterial growth?
By promoting bacterial reproduction
By enhancing host immune response
By increasing the virulence of bacteria
By disrupting cell walls or protein synthesis
By disrupting cell walls or protein synthesis
Which type of bacteria is characterized by a thicker cell wall that stains purple?
Gram-positive
Gram-negative
Cocci
Bacilli
Gram-positive
What mechanism allows bacteria to develop resistance through DNA transfer?
Natural mutation
Bactericidal action
Virulence factors
Plasmid transfer
Plasmid transfer
Which antibiotic is known for its broad-spectrum bacteriostatic effects and is not recommended for pregnant women or children under 8?
Penicillin
Macrolides
Aminoglycosides
Tetracyclines
Tetracyclines
What is the main function of biofilms in bacterial colonies?
Enhance virulence
Facilitate antibiotic absorption
Promote growth in isolation
Protect against treatment
Protect against treatment
Which of the following antibiotics works primarily against gram-negative bacteria by inhibiting DNA gyrase?
Ciprofloxacin
Gentamicin
Amoxicillin
Isoniazid
Ciprofloxacin
What term describes the ability of a pathogen to establish an infection successfully?
Pathogenicity
Invasiveness
Virulence
Resistance
Invasiveness
What is one of the CDC's strategies to combat antibiotic resistance?
Encourage extensive antibiotic use
Promote self-medication
Limit hygiene practices
Use culture sensitivity testing
Use culture sensitivity testing
Which class of antibiotics is primarily bactericidal by disturbing cell wall synthesis?
Macrolides
Tetracyclines
Cephalosporins
Aminoglycosides
Cephalosporins
Which of the following infections can be caused by Mycobacterium tuberculosis?
Bacterial vaginosis
Cholera
Candidiasis
Tuberculosis
Tuberculosis
What is the role of Isoniazid in tuberculosis treatment?
Only used in the last phase of treatment
Only used for drug-resistant TB
Recommended for all bacterial infections
First-line medication in combination therapy
First-line medication in combination therapy
What does the term 'virulence' refer to in the context of pathogens?
The ability to enter the body
The speed of infection onset
The types of bacteria present
The number of organisms required for infection
The number of organisms required for infection
Which antibiotic is a combination drug that includes Amoxicillin?
Bactrim
Cefazolin
Neomycin
Augmentin
Augmentin
Why is drug-resistant TB a significant concern among HIV/AIDS patients?
They require longer treatment periods
They often respond poorly to all antibiotics
They have higher exposure rates to allergies
Their immune system is severely compromised
Their immune system is severely compromised
What are common pathways for pathogens to enter the human body?
Oral, skin-to-skin contact, and inhalation
Ingestion only
Oral, nasal, and broken skin
Insect bites
Oral, nasal, and broken skin
Which antibiotics are usually classified as last-resort drugs due to their broad-spectrum effects and resistance to beta-lactamase?
Cephalosporins
Carbapenems
Fluoroquinolones
Penicillins
Carbapenems
What is a significant characteristic of gram-negative bacteria compared to gram-positive bacteria?
They can easily establish infections
They always cause disease
They do not require antibiotics
They have a thinner cell wall
They have a thinner cell wall
Which type of antibiotics includes Erythromycin as a common example?
Tetracyclines
Aminoglycosides
Sulfonamides
Macrolides
Macrolides
What is the impact of completing antibiotic courses as advised?
It leads to increased side effects
It enhances the virulence of the bacteria
It reduces the effectiveness of antibiotics
It prevents the development of resistance
It prevents the development of resistance
Which phase of tuberculosis treatment usually takes the longest time to complete?
Phase 1
Exposure phase
Phase 2
Prophylaxis phase
Phase 2
What do aminoglycosides like Gentamicin primarily target?
Anaerobic bacteria
Mycobacterium species
Fungal infections
Gram-negative bacteria
Gram-negative bacteria
During which phase of TB treatment is Isoniazid and Rifampin taken 2-3 times weekly?
Phase 1
Prophylactic phase
Initial phase
Phase 2
Phase 2
Which of the following statements is true about the potential consequences of antibiotic misuse?
It can lead to antibiotic resistance
It can prevent infections
It can enhance the effectiveness of antibiotics
It has no impact on health
It can lead to antibiotic resistance
What is the role of virulence in the pathogenicity of a germ?
It helps the germ replicate quickly
It weakens the host's immune response
It allows the germ to enter the bloodstream
It determines the severity of an infection
It determines the severity of an infection
In what way do tetracyclines interact with elements in the body?
They interact with calcium and iron
They release toxins
They enhance cell wall synthesis
They improve immune response
They interact with calcium and iron
What defines the 'invasiveness' of a pathogen?
Its ability to overcome host defenses
Its ability to grow in any environment
Its ability to spread quickly
Its ability to replicate inside a host
Its ability to overcome host defenses
Which of the following best describes the role of fluroquinolones?
They disrupt protein synthesis
They inhibit cell wall formation
They inhibit DNA gyrase
They prevent folic acid synthesis
They inhibit DNA gyrase
What is considered a key advantage of using cephalosporins?
They have improved effectiveness against gram-negative bacteria over generations
They provide a narrow spectrum of activity
They can be used indiscriminately
They are cheap and easy to produce
They have improved effectiveness against gram-negative bacteria over generations
Why are drugs like Augmentin considered an advancement in antibiotic treatment?
They are effective against only bacterial infections
They are not affected by resistance mechanisms
They are only useful for gram-positive bacteria
They combine two antibiotics to enhance effectiveness
They combine two antibiotics to enhance effectiveness