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homeostasis
negative feedback loops
Information flow
Sensory receptors
sensory neurons
control center
motor neurons
effectors
sensory receptors
general vs specific senses
sensory neurons
travel in nerves
control center
spinal cord and brain
motor neurons
travel in nerves
effectors
muscles and glands
negative feedback loops
responds to counteract a change
negative feedback loop: three parts
sensors/receptor
integrator/control center
effector=carry out commands
negative feedback example
blood clotting
childbirth contractions
withdrawal reflex touching a hot stove
positive feedback loop
responds to amplify a change. break in blood vessals→ damaged cell release chem.→ clotting begins→wall cause bleeding
Santiago Ramon y Cajal
fathered modern neuroscience. learned method staining while a prof. in barcelona
Nervous System
withdrawal reflex arc
Nervous System steps
Sensory receptors
sensory neuron
central N.S
Motor Neuron
effector
Sensory receptors
detects stimulus + converts that energy to an electrical signal. Destined for the central N.S
Sensory Receptors( general vs Special)
general- felt all over the body.
ex)- touch, pressure, temp,pain detected by free nerve endings
Sensory receptors ( general vs special)
special- have dedicated organ in head
ex)- vision, smell, taste, hearing, equilibrium
hearing and equilibrium= mechanic receptors
Sensory neuron
carries info from sensory receptor to Central N.S.
travels in bundles=nerve
nerve
bundle of axons in periphillis
Spinal vs Cranial nerve
Central N.S
spinal cord. Neurons have synapses with motor neurons
Central N.S
spinal cord function-integrate reflexes+ connect spinal nerves to brain( so up or down)
Central N.S
Brain. Function= conscious + subconscious control of skeletal MT. Controls cardiac MT, Smooth MT,+ glands
Central N.S
brainstem=breathing, basic body functions
Central N.S
meninges= three layers of membranes that protect the brain and spinal cord
Motor Neurons
carries “command” info from spinal cords(or brain) to effector. Travel in nerves.
Effector
skeletal MT that contracts to withdraw from pain( or cardiac MT or smooth MT or gland)
Endocrine System
Tissue= ET specialized for secretion of hormones
Hormones= chem.messengers that travel in blood, only bind to their target cells+ deliver signal to do something
function=3c’s
wireless
negative feedback loops
controlled by the hypothalamus
Hypothalamus
by controlling the pituitary gland secretes growth hormone and oxytocin
growth hormone
skeletal MT + bone tissue(synthesis targets)
Oxytocin
targets mammary glands(release milk)
smooth MT of uterus (contract)
thyroid gland
controls metabolism + heat production
Thyroid gland (hypothyroidism)
underactive
cause tiredness and weight gain
feel cold
thyroid gland does not make enough thyroid hormone
Thyroid gland(hyperthyroidism)
overactive
weight loss, increased metabolism
feel hot
make too much thyroid hormone
adrenal gland
secrete adrenaline
adrenaline
stimulates sympathetic response( emergencies)
increase heart rate + beat force
dilate arterioles in lungs + skeletal MT
dilate bronchioles to increase ventilation
Pancreas
secretes 2 hormones to regulate blood glucose levels
insuline
glycogen
Insulin
lowers blood glucose levels by stimulating liver + skeletal MT to take up glucose + store it as glycogen
Glucagon
raise blood glucose by stimulating liver to breakdown glycogen+ release glucose into blood
Biological sex
anatomy of sex organs
influenced by:
chromosomes→ anatomy→ hormones
Biological male, female, intersex
Anatomy
sex organs= genitalia
genitalia
gonads
Gonads
produce gametes + secrete hormones
gametes for biological male
sperm
Gonads for biological male
testes. sex hormones + estrogen
Sperm
made by the spermatogenesis in the seminiferous tubules
ducts for biological male
epididymis
tube
ejaculated from tail
epididymis
sperm storage, maturation + reabsorption( if necessary)
Male tube
20 ft long, takes 30 days
Glands for biological male
prostate
Vas deferens
travels up thru inguinal canal, behind bladder, merges with the seminal vesticles
Make most of the seminal fluid( includes fructose)
Urethra of biological male
passes prostate( adds more seminal fluid including clotting factors), then thru pelvic floor muscles, then thru penis→ out( at external urethral orifice)
External male genatilia
scrotum
penis
penis
shared organ between urinary + reproductive system
senstation
glans(tip) protected by prepuce( foreskin)
functions-
protection
immunity
sensation
Urinary Tract Infection
Not an STI
Urinary Tract Infection
kidney provides urine→ureter transports urine towards urinary bladder→ urinary bladder temporarily stores urine prior to elimination→ urethra conducts urine to the exterior
Most likely caused by e.coli bacteria
treated with antibiotics
STI
caused by bacteria or viruses
Bacterial STI’s
gonorrhea
chlamydia
syphilis
Viral STI’s
not alive
cannot be treated with antibiotics
Viral STI’s
genital herpes
genital warts
HIV
Gonorrhea
asymptomatic
puss like discharge
Chlamydia
MOST COMMON
Syphalis=3 stages
stage 1= chancre(painless sore)
stage 2= body wide rash
stage 3= skin ulcers, neurological degeneration, death
Gonorrhea and chlamydia can lead to…
Pelvic inflammatory disease
genital herpes
caused by herpes Synplex virus
Genital herpes 1= oral
Genital herpes2= genital
Genital warts
caused by Human Papilloma Virus
150 different strains
HPV vaccine
Gardosil protects against 4 strains of HPV:
2 that protects 90% of genital warts
2 that protects 70% of cervical cancer
HIV( Human immunodeficiency virus)
takes over helper T lymphocytes, leads to acquired immunodeficiency syndrome (AID’s)
Theory of Biological evolution
change in the gene pool of a population over time
microevolution
microevolution
changes accumulate overtime and can lead to large-scale change: macroevolution
Macroevolution examples
new adaptation appears
new species appears= speciation
Popular myths
Scientists investigate or dispute the potential existence of gods/deities
its impossible to be both an evolutionary biologist and a religious believer
Humans descended from monkeys
Evolution is scientifically controversial
Evolution is” just a theory” (not fact)
fact
something known to exist or have happened
3 features of all populations
genetic variation→ all based on mutation
competition for limited resorces
hereditary= mutations are heritable if they arise in gametes
heritable
something that can be inherited
How does a gene pool change over time?
genetic drift
gene flow
Genetic drift
change in gene pool of a population due to a random chance
ex) bottleneck effect
ex) bottleneck of northern elephant seals= hunted to almost extinction, only 20 left that repopulated
ex) founder effect in Darwin Finches= got blown away in wind storm
gene flow
change in a gene pool of a population due to migration in/out of that population
homologous structures
are those that derive from the same embryonic structures
homologous structures
testis—ovaries
penis— clitoris
nipple— nipple
biological female anatomy(gonads)
ovaries make eggs + sex hormones= estrogen + progesterone
eggs( in gonads)
develop in follicles on a cycle(± 28 days)
1 egg/cycle(or 2 ) released from follicle= ovulation
bio. female anat.( Ducts)
uterine tube
“Sucks up” ovulated eggs with ciliated cells
typical site for fertilization
cilia sweep embryo to the uterus
ectopic tubal pregnancy
tubal ligation
bio female anat. (Uterus)
where embryo implants + develops fetus
implants
lining is welcome: glycogen rich mucus + lots of spiral capillaries
+ blood= menses
endometrium
uterus
neck= cervix( access thru vagina)
thick walls of smooth MT— has cervical canal= dilates to 10cm
bio of female anatomy (vagina)
birth canal
vaginal orifice= opening
bio female anatomy external genitalia (vulva)
labia majora + labia minora= protection
clitoris homologous to penis, made of 3 erectile bodies →fxn: sensation
female anatomy externial genetilia( glands)
accessory glands= lube
mammary glands= secrete milk
homologous reproductive structure
structure—Male—female
gonads—testes—ovaries
gametes—spermatozoa—ova
hormones—testosterone—estrogen
erectile organ—penis—clitoris
glands—seminal vesicle—accessory glands
—prostate and Cowper glands
external—penis—clitoris
genetilia—scrotum—labia majora
contraception
preventing pregnancy
contraception
IUD(intrauterine device)
surgical sterilization(male/female)
birth control implant
birth control shot
birth control pill condom
sponge'
transdermal patch
emergency contraception
hormonal methods
suppress ovulation
thicken cervical mucus
thin the endometrium
barrier methods
dont let sperm get past
2 more mechanisms for bio.evol.(sexual selection)
change in gene pool of a pop. over time due to non random mating
ex. sage grouse—lekking
ex. superb lyrebird—song/chirping
ex. peacock spider—dancing
2 more mechanism for biol. evol.(natural selection)
change in gene pool(allele frequency) of a pop. over time due to environmental selective pressure
*some individuals in a pop. leave more offspring than others= those individuals are more fit
fitness
measure of an individual’s genetic contribution to the next generation
*focus on heritable characteristics that increase an individual’s ability to survive + reproduce in a particular environment → adaptation
evidence for biol. evol. (4 categories)
see evolution in action(artificial selection)
humans are the selectors
ex: dog breeding
ex. crop development
evidence for biol. evol.(4 categories)
see evolution in action(resistance)
pop. develops resistance to____
ex. bacteria to antibiotics
ex. viruses to antiviral meds
ex. weeds to herbicides
evidence for biol. evol. (4 categories)
homology
results from common ancestry
anatomic homology
ex. forelimbs of vertebrates
vestigial structures= reduced or no function
ex; boa hind limbs+ pelvic bones
ex. baleen whale hind limbs
ex. blind mole rats eyes
ex humans(arrector pili muscles(makes hair stand up), tailbone, appendix, palmaris muscle+ calf muscle)
homologous structure
characteristics seen in different species that result from common evolutionary ancestry
embryological homology
ex. common development patterns
ex. human embryo w/ tail, notochord, pharyngeal gill slits
molecular homology
ex. ATP, proteins, DNA, RNA
ex. E pathways: cell resp., photosynthesis