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These question-and-answer flashcards cover the key infectious-disease concepts, organisms, signs, diagnostics, treatments, and control measures presented across the lecture notes.
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When does the incubation period of a disease begin and end?
It begins upon exposure to the pathogen and ends with the appearance of the first signs or symptoms.
Tetanus
Involuntary spasm ( inducing bacterial infection )
Lock jaw
Tetanus also known as
3 days to 1month
Incubation period for tetanus
Rissus sardonicus
Pathognomonic sign for tetanus
Laryngospasm, Opisthotonus, spastic paralysis
Other pathognomonic sign for tetanus
Wound culture
Confirmatory sign for tetanus
Spatula test
Alternative test for tetanus
(+) gag reflex
Negative response (-) of spatula test
Bites the material
Positive response for spatula test
DPT/ Pentavalent (6-20-24 weeks)
Tetanus toxoid atleast 2 shots (no wound)
Tetanus anti-toxin - presence of wond
Vaccination for tetanus
What characterizes the prodromal period of a disease?
It starts with the first vague signs or symptoms and ends when more generalized, diagnosable signs and symptoms appear.
HydrogenPeroxide
Betadine thin dressing only
Wound care for tetanus
Non- stimulating environment (quiet, dim-lit, well-ventilated)
Nursing intervention for pt. With tetanus and to avoid seizure
(+)seizure
(+) Opisthotonus
Stay if seizure occurs
side lying or just add supporting layers like pillows
High Caloric diet
Diet for tetanus pt.
Metronidazole, alternative is tetracycline
Drug of choice for tetanus
Droplet
Mode of transmission of meningitis and rabies
During which stage of disease do pathognomonic signs peak?
The Illness phase.
Face mask and PPE
Control measures of meningitis
Remittent-fever
Onset of seizure
Altered respiratory
WOF danger signs for meningitis
VS
PERRLA
GCS
Frequent neurological checking in meningitis
Valsalva manuever
Bearing down
Carrying Heavy object
What to avoid in pt.with meningitis?
High fiber diet
Diet for pt with meningitis
First stage (Dog: Dumb, Human: Prodromal phase)
What stage in rabies infection when the dog show signs withdrawn and hiding. Human shows tingling sensation and photophobia
Second stage (Dog: Furious, Human: Excitement phase)
What stage in rabies infection when the dog show signs of fight &bite, hyper salvation and hydrophobia. Human shows laryngospasm, hydrophobia, aerophobia, and maniacal behavior.
Third stage (Human & Dog: Paralytic)
What stage in rabies infectionBoth human and dog experiences cardiopulmonary arrest
10 day observation of dog
Brain biopsy
Fluorescent rabies anti body
Diagnostic test for rabies
Wash with detergent soap with running water for 10-15 minutes
Bayabas as anti septic
Consult ABC
First aid for rabies
ERIG (EQUINE RABIES IMMUNOGLOBULIN)
HRIG (HUMAN RABIES IMMUNOGLOBULIN)
PVRV
VACCINES FOR RABIES
CATEGORY 2
WHAT CATEGORY WHEN BITTEN CHEST TO DOWN
CATEGORY 3
WHAT CATEGORY WHEN BITTEN NECT AND HEAD AND ALSO ANYWHERE BUT WITH OOZING WOUND
CATEGORY 1
WHAT CATEGORY HAS NO VISIBLE WOUND JUST REDDENED IN THE SKIN ONLY
Department of Agriculture
Responsible for dog vaccination
Away from the CR/sink
Where should position the pt infected with rabies
Cover IV lines
What to do when pt experiencing hydrophobia
Restraint
What to do when pt experiencing maniacal behavior rabies (+)
Legio debilitons
Causative agent for poliomyelitis
Abortive
Last 72 hours with fever and sore throat
Subclinical
Asyptomatic
Stool exam
Lumbar tap
Electro myelogram
Muscle grading
Diagnostic test for poliomyelitis
Bulbar
Brainstem
CN 9 and CN 10
Spinal paralytic
Spine (limbs, intercostal muscle)
Bulbospinal
Both spine and brain affected
OPV (oral)
IPV (IM)
Control measures for polio
Enteric precaution
Promptly isolating the patient in a single room with closed doors.
Using gloves and an apron for any procedure involving contact.
Handwashing is compulsory when any direct contact occurs with feces or vomitus. Using alcohol-hand rub alone is insufficient.
Bethanicol Chloride- prevents respiratory depression
Pleonaril - inhibits viral entry in CNS
Drug of choice for poliomyelitis
Do not massage only warm compress
Bet should not saggy and should be firm
Management for poliomyelitis
anesthesia
Skin discoloration
Anhidrosis- loss of sweat
Early manifestations of leprosy
Madarosis- falling of eyebrows
Lagopthalmus- inability to close eyes
Lion like appearance
Contractures
Wound does not heal
Gynecomastia- male big chest
6months - 8 yeaars
Incubation period of leprosy
Dog Vaccination
Pet ownership responsibility
Dog bite victim management
Control measures for rabies
Which stage of disease involves gradual disappearance of signs and symptoms and recovery?
The Convalescence stage.
Slit skin smear
Confirmatory test for leprosy
CRT ( lepromin reaction test )
Test for communicability in leprosy (8-10 days result to wait)
Droplet and contact-prolonged exposue
MODE OF TRANSMISSION OF LEPROSY
POSITIVE IN LRT WITH RASHES
NON-COMMUNICABLE FOR LEPROSY
NEGATIVE IN LRT WITH NO RASHES
VERY COMMUNICBLE FOR LEPROSY
BCG
Vaccine for Leprosy
Rifampicin
Ofloxacin
Minocycline
Prophylaxis for leprosy
What is the defervescence period?
A stage where complications may set in and can lead to death if not managed.
What bacterium causes tetanus (lockjaw)?
Clostridium tetani.
What is the incubation period for tetanus?
Approximately 3 days to 1 month.
How does tetanus usually enter the body?
Through entry of spores into broken or intact skin, activating once the wound is closed and anaerobic.
Drug of choice for treating tetanus?
Metronidazole (avoid alcohol during therapy).
What is meningitis?
Inflammation of the meninges, also called cerebro-spinal fever.
Causative agent of bacterial meningitis highlighted in lecture?
Neisseria meningitidis.
Incubation period for meningococcal meningitis?
2–10 days.
Mode of transmission for meningococcal meningitis?
Droplet spread.
Pathognomonic sign of meningitis
Nuchal rigidity (stiff neck).
Two classic physical signs used to screen for meningeal irritation
Brudzinski’s sign (neck flex → hip/knee flex) and Kernig’s sign (inability to fully extend knee with hip flexed).
Preferred diagnostic test for meningitis and its expected finding in bacterial cases
Lumbar puncture; cloudy/turbid cerebrospinal fluid.
Why should MRI be done before lumbar tap in suspected meningitis?
To rule out markedly raised intracranial pressure, which is a contraindication to lumbar puncture.
First-line antibiotics for bacterial meningitis
Penicillin G, a cephalosporin, or chloramphenicol.
Prophylactic drug for close contacts of meningococcal cases
Rifampicin.
Preferred patient position in acute meningitis to ease breathing and ICP
Semi-Fowlers with a non-stimulating environment.
What viral infection causes rabies and what is its other name?
Rhabdovirus infection, also called hydrophobia, la rage, or lyssa.
Incubation period for rabies in humans
About 2–8 weeks (variable).
Primary mode of rabies transmission
Saliva droplets via animal bite or lick on broken skin.
Two epidemiologic categories of rabies
Canine (domestic dogs) and sylvatic (wild animals).
Three clinical stages of rabies in humans
Prodromal, Excitement (furious), Paralytic.
Classic diagnostic finding on brain biopsy in rabies
Negri bodies.
First-aid management of an animal bite
Wash with detergent/antibacterial soap under running water for 10–15 minutes, then seek care at an Animal Bite Center.
Name the equine and human preparations for passive rabies immunization
ERIG (Equine Rabies Immunoglobulin) and HRIG (Human Rabies Immunoglobulin).
Poliomyelitis is also known as and causes what type of paralysis?
Heine-Medin disease or infantile paralysis; causes flaccid paralysis.
Mode of transmission of poliovirus
Fecal-oral route.
Incubation period of poliomyelitis
7–21 days.
Difference between minor and major forms of polio
Minor (subclinical or abortive) has mild or no paralysis; Major forms include non-paralytic and paralytic manifestations.
Tripod position and Hoyne sign indicate which form of polio?
Non-paralytic or early paralytic polio with meningeal irritation.
Which cranial nerve involvement in bulbar polio threatens cardiopulmonary function?
Cranial nerve X (vagus nerve).
Essential isolation precaution for hospitalized polio patients
Single-room isolation with closed doors; gloves/apron for contact; strict handwashing (alcohol rub alone insufficient).
Confirmatory test for leprosy (Hansen’s disease)
Slit-skin smear.
BCG vaccine provides some protection against which two diseases?
Tuberculosis and leprosy.
Standard multi-drug regimen for leprosy includes which three drugs?
Rifampicin, Dapsone, and Clofazimine.
Tuberculosis is also called Koch’s infection; name its primary causative organism
Mycobacterium tuberculosis.
Most sensitive confirmatory laboratory test for TB cited in notes
GeneXpert (CB-NAAT).
Interpretation of Mantoux test: induration ≥10 mm suggests what?
TB exposure in the general population (≥5 mm for immunocompromised).
What first-line TB drug can cause red-orange body secretions?
Rifampicin.
Which TB drug’s major side effect is peripheral neuritis, and how is it prevented?
Isoniazid; prevented with vitamin B6 (pyridoxine) supplementation.
Define DOTS in TB control
Directly Observed Treatment, Short-course—patient takes drugs under supervision.