Cell Communication

What are the 2 types of cellular communication?

1) Intercellular signaling communication between cells

2) Intracellular signaling communication within cells

What are the 4 forms of signaling?

1) Autocrine: Cell talks to itself

2) Direct across gap junctions: Ligands pass from one cell to another through small channels

3) Paracrine: Signals act locally between cells

4) Endocrine: Signals act between long distances

What are the 2 types of receptors?

1) Intracellular receptors: found in the cytoplasm

2) Cell-surface receptors: Found on the cell surface; integral proteins

What are the 3 types of cell-surface receptors?

1. Enzyme-linked receptors

2. G-protein coupled receptors

3. Ligand-gated ion channels

What are the 2 types of signaling molecules?

1) Small hydrophobic ligands: Used with intracellular receptors

2) Water-soluble ligands: Used with cell-surface receptors

What are the 3 stages of cell signaling?

1) Receptor activation- Signaling molecules bind to the receptor

What are the 3 stages of cell signaling?

2) Signal transduction

- Once the ligand binds to the receptor, the signal is transmitted through the membrane into the cytoplasm

What is a signaling pathway? chain of events set off by the activated receptor

What are the 3 stages of cell signaling?

3) Cellular response

- Different responses possible; could include programmed cell death

What is this called? Apoptosis