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52 Terms

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Lymph

A clear watery liquid formed from interstitial fluid found between cells.

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Interstitial fluid

Fluid found between cells; 90% diffuses back into capillaries and 10% enters lymphatic vessels.

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Lymphatic vessels

Vessels that carry lymph to lymph nodes.

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Lymph capillaries

Lymph vessels with 'dead ends' that are lined with overlapping epithelial cells.

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Lymph nodes

Capsules of connective tissue that filter lymph and contain germinal centers.

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Germinal centers

Areas in lymph nodes where rapid mitosis of immune cells occurs.

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Afferent vessels

Lymphatic vessels that bring lymph to lymph nodes, causing it to slow down.

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Efferent vessels

Lymphatic vessels that carry lymph away from lymph nodes.

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Right lymphatic duct

One of the large ducts in the chest that carries lymph.

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Thoracic duct

The main lymphatic duct that drains lymph into the venous circulation.

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Spleen

An organ that filters blood and is located in the upper left abdomen.

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White pulp

Part of the spleen composed of lymphatic tissues and lymph nodules for filtering blood.

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Red pulp

Part of the spleen that removes worn out red blood cells and serves as a reservoir for stored blood.

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Thymus

An organ associated with the endocrine and lymphatic systems, responsible for T-lymphocyte maturation.

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Thymic education

The process where T-lymphocytes learn to recognize foreign invaders.

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MALTS

Mucosa-associated lymphoid tissues that can be scattered or bundled together.

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Tonsils

A protective ring of lymphoid tissue that traps foreign invaders.

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Peyer's patches

Lymphoid tissues in the intestine that filter bacteria from food.

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Appendix

A structure that restricts bacteria to the GI tract.

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Innate immunity

The body's initial defense against pathogens, including external and internal mechanisms.

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Phagocytes

Immune cells that 'eat' foreign invaders (e.g., neutrophils and macrophages).

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Natural killer cells

Cells that destroy infected or abnormal body cells based on the absence of 'self' receptors.

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Complement proteins

Proteins that work with other defenses to lyse bacteria.

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Interferons

Warning signals secreted by virally infected cells.

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Cytokines

Chemical signals used to help cells communicate during an immune response.

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Specific immune response

An immune response triggered by antigens leading to the activation of lymphocytes.

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Humoral immunity

Immune response mediated by B cells producing antibodies.

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B lymphocytes

Immune cells that recognize foreign antigens and can produce memory B cells.

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Plasma B cells

B cells that neutralize or immobilize antigens and activate macrophages.

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Active immunity

Immunity developed through the production of the individual's own antibodies.

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Passive immunity

Immunity acquired through the transfer of antibodies from another individual.

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Natural immunity

Immunity acquired through infection (e.g., contraction of flu virus).

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Artificial immunity

Immunity acquired through medical intervention (e.g., flu vaccine).

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APCs (Antigen-Presenting Cells)

Cells that engulf antigens and present them to other immune cells.

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MHC-2

A receptor on APCs where antigens are presented for T-cell recognition.

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Cell mediated response

The immune response mediated by T cells after recognizing foreign antigens.

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Helper T cells

T cells that are activated by APCs and stimulate other immune cells.

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Cytotoxic T cells

T cells that directly kill infected cells.

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Regulatory T cells

Cells that release chemicals to slow down the immune response after the threat is eliminated.

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Memory T cells

T cells that remain after an infection for a faster response upon re-exposure.

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Vaccines

Substances that mimic the first infection, preparing the immune system for future encounters with an antigen.

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Plasma B cells functions

Neutralization, immobilization (agglutination), and activation of macrophages.

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Swift response

The quick action of memory B cells upon re-encountering the same antigen.

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Specific antibody production

The generation of antibodies tailored to specific antigens.

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Lymphoid organs

Organs such as spleen and thymus that contribute to immune response.

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Edema

Swelling caused by fluid accumulation, aiding macrophages during inflammation.

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Pyrogenic response

Fever response induced by pyrogens in response to infection.

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Basophils and mast cells

Cells that release histamine to promote inflammation.

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Pathogen trapping

The action of mucous membranes in trapping and sweeping pathogens.

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Defensive barriers

Mechanical and chemical means of preventing pathogen entry, such as skin and mucous membranes.

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Lymphatics

The network of vessels that transport lymph throughout the body.

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Antigen recognition

The ability of B and T cells to identify foreign substances in the body.