Thymus-independent antigens: TI-2 antigens

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What are Thymus-independent antigens (TI-2)?

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Antigens that activate B cells through recognition of repetitive polysaccharide components on bacterial cell walls.

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How do immunoglobulins recognize TI-2 antigens?

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They recognize repetitive polysaccharide components on bacterial cell walls.

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What are Thymus-independent antigens (TI-2)?

Antigens that activate B cells through recognition of repetitive polysaccharide components on bacterial cell walls.

2
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How do immunoglobulins recognize TI-2 antigens?

They recognize repetitive polysaccharide components on bacterial cell walls.

3
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What happens when membrane immunoglobulins cluster on B cells?

Clustering triggers B-cell activation.

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Does B-cell activation require anything beyond clustering of immunoglobulins?

Yes, it requires costimulation of the B-cell coreceptor.