Thymus-independent antigens: TI-2 antigens
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Last updated 1:47 AM on 2/25/25
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4 Terms
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What are Thymus-independent antigens (TI-2)?
Antigens that activate B cells through recognition of repetitive polysaccharide components on bacterial cell walls.
2
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How do immunoglobulins recognize TI-2 antigens?
They recognize repetitive polysaccharide components on bacterial cell walls.
3
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What happens when membrane immunoglobulins cluster on B cells?
Clustering triggers B-cell activation.
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Does B-cell activation require anything beyond clustering of immunoglobulins?
Yes, it requires costimulation of the B-cell coreceptor.
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