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ID - lack of iron (blood loss or diet)
AA - bone marrow failure (affects blood cell production)
PA - lack of Vitamin B12 (poor absorption - autoimmune)
Differentiate ID, AA and PA on CAUSE
ID - fatigue, weakness, pale skin, SOB
AA - Fatigue, frequent infections, easy bruising
PA - Fatigue, pale/yellow skin, nerve damage (tingling or numbness)
Differentiate ID, AA and PA on SYMPTOMS
ID - microcytic (small), hypochromic (pale) RBC
AA - pancytopenia (reduction in ALL blood cells)
PA - macrocytic (large), hypersegmented RBC
Differentiate ID, AA and PA on APPEARANCE
ALL DECREASED
Differentiate ID, AA and PA on HgB levels
ALL DECREASED
Differentiate ID, AA and PA on RBC levels
ID - normal
AA - decreased
PA - normal
Differentiate ID, AA and PA on WBC & Platelet counts
ID - low serum ferritin and iron, HIGH TIBC
AA - low reitculocyte count, hypocellular bone marrow
PA - low serum B12, high homocysteine, positive Schilling test
Differentiate ID, AA and PA on KEY LAB FINDINGS
ID - poor diet, pregnancy, blood loss
AA - radiation, chemo, autoimmune disorders
PA - autoimmune disorders, gastric surgery, older age
Differentiate ID, AA and PA on Risk Factors
ID - iron supplementation, dietary changes
AA - bone marrow transplant, immunosuppressive treatment
PA - vitamin B12 injections, dietary supplementation
Differentiate ID, AA and PA on TREATMENT
ID - good with treatment, need to address underlying cause
AA - depends on severity, life threatening without treatment
PA - good with proper management of B12 deficiency
Differentiate ID, AA and PA on PROGNOSIS
