(PART 2) Calamine + Zinc Oxide Ointment

Calamine + Zinc Oxide Ointment
Cleansing Cream

Semi-Solid Preparations

Calamine
Zinc Oxide
Mineral Oil
White Ointment

Ingredients for Calamine + Zinc Oxide Ointment

White Wax
White Petrolatum

Ingredients for White Ointment

White Ointment 

- Base: A vehicle for medications in various topical pharmaceutical formulations. Allows for the incorporation and even distribution of active pharmaceutical ingredients(APIs).
- Emollient: Acts as a moisturizer, that fill in the gaps between dead skin and replacing natural lipids.

Base for Medication
Emollient

Properties of White Ointment

Emollient
Humectant
Occlusive

Types of Moisturizer

Humectant

Types of Moisturizer
Are hydrophilic, and help draw water from the dermis to the epidermis.

Emollient

Types of Moisturizer
Reduce transepidermal water loss by filling in gaps between gaps between dead skin cells and replacing absent natural lipids.

Occlusive

Types of Moisturizer
Prevents water loss by forming a hydrophobic barrier over the stratum corneum.

Cera Alba
Bleached Beesewax

White Wax is also known as?

White Wax

Ingredients for White Ointment
- Derived from the honeycomb of the honeybee (Apis mellifera).
- Gives body and firmness to the ointment so it isn’t too soft.
- Helps the ointment hold its shape and prevents it from melting or separating easily
- Provides a thin coating on the skin, adding mild emollient effects.

Consistency/ Stiffening Agent
Stabilizer
Protective Property 

Properties of White Wax

White Petrolatum

Ingredients for White Ointment
- Geological Source (Purified Petroleum Jelly)
- Main component providing the smooth, greasy texture.
- Softens and soothes dry or irritated skin by forming a protective occlusive barrier that prevents water loss.
- Shields skin from environmental irritants and helps retain moisture
- Serves as the base into which active ingredients(drugs) can be incorporated
- Non-Comedogenic

Geological Source (Purified Petroleum Jelly)

Origin of White Petrolatum

Petrolatum Album

White Petrolatum is also known as?

Base/ Ointment
Emollient
Protective Agent
Vehicle for Medicaments 
Non- Comedogenic 

Properties of White Petrolatum

Calamine + Zinc Oxide Ointment

- Used for the relief of itching and irritation caused by insect bites, chickenpox, and minor rashes.
- It also helps in the management of mild skin inflammation, such as contact dermatitis and eczema.
- By forming a protective barrier, it shields chafed or irritated skin, while its astringent property assists in drying oozing lesions.

Calamine 

Ingredients for Calamine + Zinc Oxide Ointment
- Prepared from zinc carbonate and small amounts of ferric oxide (gives its pink color).
- Antipruritic (relieves itching), astringent (dries oozing skin), and soothing agent.

Zinc Oxide 

Ingredients for Calamine + Zinc Oxide Ointment
- Obtained by oxidizing metallic zinc or roasting zinc ores (like zincite or smithsonite).
- Protective barrier, mild antiseptic, astringent, promotes healing of skin.

Mineral Oil 

Ingredients for Calamine + Zinc Oxide Ointment
- Derived from the purified liquid fraction of petroleum (highly refined hydrocarbon oil).
- Emollient (softens skin), vehicle for dispersion of powders, prevents paste from drying out.

White Ointment

Ingredients for Calamine + Zinc Oxide Ointment
- White Petrolatum: Purified semisolid hydrocarbons from petroleum residue.
- Base that gives consistency, occlusive protectant to prevent moisture loss, enhances contact of actives with skin.