[ANAL-LAB-MID-01-PT1] TABLET THICKNESS AND DIAMETER AND ETC.

THIS FLASH CARDS IS ABOUT ANALYSIS; TABLET THICKNESS AND DIAMETER AND ETC.

Tablet Thickness

The measurement of a tablet from one flat surface to the opposite flat surface.

Tablet Diameter

The distance across the widest part of the tablet (round tablets) or the longest dimension (oval/capsule-shape tablets).

Round Tablets

What type of tablets has the longest part?

Oval/Capsule-shaped Tablets

Which type of tablets have the longest dimension?

• Dosage Uniformity

• Patient Compliance

• Batch Consistency

• Avoid Packaging Problems

• Regulatory Compliance

• Avoid Calibration Issues

What are the six (6) importance of tablet thickness and diameter?

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Dosage Uniformity

WHAT IS THE IMPORTANCE?

Ensures each tablet contains the correct amount of active ingredient.

Patient Compliance

WHAT IS THE IMPORTANCE?

Tablets are easier to take when size and shape are consistent.

Batch Consistency

WHAT IS THE IMPORTANCE?

All tablets in a batch have uniform thickness and diameter.

Avoid Packaging Problems

WHAT IS THE IMPORTANCE?

Uniform tablets fit properly in packaging without damage.

Regulatory Compliance

WHAT IS THE IMPORTANCE?

Meets standards for tablet size, weight, and quality.

Avoid Calibration Issues

WHAT IS THE IMPORTANCE?

Consistent tablet dimensions prevent errors in production equipment.

• Punch and Die Size

• Granule Properties

• Compression Force

• Machine Settings and Tooling Wear

• Tablet Formulation

• Environmental Conditions

What are the six (6) Factors Affecting Tablet Thickness and Diameter?

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Punch and Die Size

FACTORS AFFECTING TABLET THICKNESS AND DIAMETER:

Determines the tablet’s final shape and dimensions.

Granule Properties

FACTORS AFFECTING TABLET THICKNESS AND DIAMETER:

Particle size, flow, and density affect tablet thickness and diameter.

Compression Force

FACTORS AFFECTING TABLET THICKNESS AND DIAMETER:

Higher or lower force changes tablet size and hardness.

Machine Settings and Tooling Wear

FACTORS AFFECTING TABLET THICKNESS AND DIAMETER:

Worn or misaligned tools can alter tablet dimensions.

Tablet Formulation

FACTORS AFFECTING TABLET THICKNESS AND DIAMETER:

Ingredients and their proportions influence tablet thickness and diameter.

Environmental Conditions

FACTORS AFFECTING TABLET THICKNESS AND DIAMETER:

Humidity and temperature can cause swelling or shrinking of tablets.

• Vernier Calipers

• Micrometer Skrew Gauge

• Automated Tablet Testing Instruments

What are the three (3) Measuring Instruments used to measure dosage forms?

Vernier Caliper

This device length, thickness, depth, and internal/external diameters of objects accurately.

External Jaws

This part of the vernier caliper measures outside dimensions.

Internal Jaws

This part of the vernier caliper measures inside dimensions.

Locking Screw

This part of the vernier caliper fixes the sliding jaw in place.

Imperial Scale

This part of the vernier caliper measures in inches.

Metric Scale

This part of the vernier caliper measures in millimeters.

Depth Measuring Blade

This part of the vernier caliper measures depth of holes or slots.