Drug Metabolism

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7 Terms

1
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What is the point of drug metabolism?

To convert lipid soluble drugs to water soluble drugs.

2
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What are prodrugs?

Drugs that enter as inactive form → gets metabolized into active form.

3
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Do all drugs need to metabolized?

No, these drugs are called hard drugs.

4
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What processes happen in phase 1?

Ozidation*

Hydrolysis

Reduction

5
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What processes happen in phase 2?

Conjugation

6
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What is the most important type of CYP450?

CYP3A4

7
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What are enzyme inducers?

They are drugs that increase Hepatic enzymes function → increase drug metabolism