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antioxidants
protect cells from damage caused by oxidation
vitamins:
E
C
A
Selenium
antioxidant vitamins
stabilize free radicals to reduce oxidative damage
antioxidant minerals
act as cofactors within enzyme systems that convert free radicals to less damaging substances that can be excreted
antioxidant food sources
blueberries, peppers, avocado, oil, spinach, almonds
beta-carotene
precursor to vitamin A
non-essential nutrient
weak antioxidant
don’t take supplements
one moluecule of beta-carotene =
2 molecules of retinol (vitamin A)
overconsumption of beta-carotene leads to…
carotenosis
beta-carotene is expressed in food as…
Retinol Activity Equivalents
how much active vitamin A is available after conversionb
beta-carotene food sources
pumpkin
sweet potato
carrot
spinach
kale
broccoli
vitamin A food sources
beef liver
egg
dairy
fortified food
vitamin C food sources
strrawberries
grapefruit
broccoli
peppers
orange
vitamin e foods
olive oil
sunflower oil
coconut oil
avocado
almonds
sodium foods
processed food
fish
eggs
cheese
potassium foods
potatoes
brussel sprouts
spinach
banana
avocado
vitamin C deficiency
SCURVY
overgrown gums & swollen
failure to heal
lack of collagen production
vitamin A deficiency
night blindness
xerophthalmia (hardening of cornea)
hyperkeratosis (hard dry skin)
impaired immunity
potassium deficiency
hyppokalemia
leg cramps
weakness
abnormal heart rhythm
tingling/numbness
phytochemicals
not nutrients, but naturally occuring plant chemicals
have antioxidant properties that neutralize free radicals
phytochemicals examples
carotenoids
flavonoids
phelonic acid
phytoestrogen
organosulfur
magnesium food sources
spinach
black beans
oat bran
brown rice
pumpkin seeds
trail mix
calcium food sources
yogurt
sardines
milk
collared greens
cheese
kale
fluoride food sources
fluorinated dental products
fluorinated water
bad calcium sources
binding factors phytates and oxalates reduce calcium absorption like leafy greens, spinach, wheat bran (high in oxalic acid) & phytates)
good sources of calcium
milk, yogurt, cheese, salmon, mackerel
calcium deficiency
osteoporosis & hypocalcemia
what minerals make up the bones
fluoride
calcium
magnesium
phosphorus
how to test bone density
DEXA scam (dual xray absorptiometry)
low concentration blood calcium
increased secretion of parathyroid hormone
causes bone & kidneys to release calcium
increased Vitamin D activation
high concentration blood calcium
inhibition of parathyroid hormone
suppression of vitamin D
dec absorption of calcium from the intestines
dec bone breakdown
dec reabsorption of calcium by kidneys
osteoclasts
break down bone
osteoblasts
build new bone
by laying down collagen components
factors that enhance vitamin D synthesis
summer months
latitude closer to equator
time of day (sunniest)
age (younger)
limit use of sunscreen
exposed skin
lighter skin
factors inhibiting vitamin D synthesis
winter months
less sunlight locations
night time
older ppl
using sunscreen
cloudy weather
darjer skin
glass and plastic
obesity
vitamin D foods
salmon
mackerel
milk w vitamin D
liver
eggs
vitamin D deficiency
rickets & osteomalacia
osteoporosis risk factors
smoking
low BMI
low calcium
low sun exposure
alcohol
amenorrhea ( no period)
low estrogen
low testosterone
falling
sedentary life
being white or asian
gender (female)
older age
heme iron
only in animal products
poultry
beef
fish
non heme iron
spinach
beans
lentils
fortified cereals
whole wheat bread
iron absorption promotes..
meat factor
stomach acid
Vitamin C
iron absorption impairs…
phytates
polyphenols
vegetable proteins
fiber
Ca 2+, Zn2, Mg2, Mn2,
low stomach acid
iron regulation
absorption is dependent on current body stores
absorb 1-2mg/d to convert our loss
absorption, transport, storage, excretion, and recycling
majority of iron is in blood
20x greater than iron in diet
iron toxicity
45mg
nausea, vomiting, diarrhea
ppl at risk: kids
Hemochromatosis: genetic disorder causing excessive iron absorption and storage
treatment: reduce dietary iron, avoid high vitamin C, and blood removal
iron deficiency
most common deficiency in the world
microcytic anemia: weakness, fatigue, headache
ppl at risk: kids, adolescent girls, premenopausal and pregnant women
poor dietart intake
iron loss in blood
diet high in fiber or phytates
low stomach acid
vitamin K
blood coagulant and bone meatbolism
phylloquinone- plant form
menaquinone- animal form (produced by bacteria in large intestine)
turnip greens
broccoli
brussel sprouts
spinach
zinc
component of enzymes (heme synthesis)
structure of protein (zinc fingers)
regulation of gene expression
absorption increases w need
decreased absorption w non-heme iron & fiber
increased w animal-based protein
zinc foods
oysters, pork, beef, crab, whole grains, enriched grains
non-specific immunity
body’s primary defense against microbes, airborne stuff, and ingested toxins
aka innate defense
intact skin and mucous membranse
stomach acid destroys food-borne bacteria
inflammatory response causes discomfort, loss of appetite, fatigue, and fever
specific immunity
directed against recognized antigens
memory cells
B & T cells
maternal antibodies
antiserum injection (snake bite)