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Cause
Lack of intrinsic factor (autoimmune destruction of gastric mucosa or surgery)
Symptoms
Glossitis (red, smooth tongue)
neuropathies (numbness, tingling, gait issues, memory problems)
Diagnosis
Macrocytic
normochromic anemia
low serum B12
antibodies to intrinsic factor
gastric biopsy.
Treatment
B12 supplementation.