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week 1
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Hypertonic infusions
Water moves out of cells into fluid.
➢ 3% Sodium Chloride
➢ 5% Sodium Chloride
➢ 10% Dextrose in Water (D10W)
Isotonic infusions
Expands intravascular (extracellular) fluid volume
➢ 0.9% Sodium Chloride (Normal Saline) (NS)
➢ Lactated Ringers (LR)
➢ Plasma-Lyte
Hypotonic infusions
Water moves from fluid into the cells, causing swelling.
➢ 0.45% NS
➢ 5% Dextrose in Water (D5W) (initially isotonic but become hypotonic in body).
Hypertonic fluids can be used to treat:
➢ Severe hyponatremia (*cautiously*)
➢ Cerebral edema
➢ Volume expansion (*cautiously*)
Things to watch for in hypertonicity:
➢ Severe hypovolemia
➢ Hypernatremia
➢ Neurological changes (demyelination)
➢ Intravenous site injury
Isotonic fluids can be used to treat:
➢ Fluid resuscitation
➢ Dehydration
➢ Surgery
➢ Mild hyponatremia
Things to watch for in isotonicity:
➢ Fluid overload (especially in heart failure patients)
➢ Metabolic acidosis (hyperchloremic)
Hypotonic fluids can be used to treat:
➢ Cellular dehydration
➢ Hypernatremia
➢ Renal excretion
Things to watch for in hypotonicity:
➢ Neurological changes (cerebral edema)
➢ Worsening hyponatremia