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animals are multicellular and have 4 different tissue types
connection, nervous, muscle, and epithelial
connective tissue
cels loosely arranged in a matrix of etracellular function and other materials secreted by connective tissue cells
loose - fibrous proteins in soft matrix, packing material, padding, fibroblasts - cells make fibers and extracellular matrix
dense - matrix is mostly collagen-tough- secreted by fibroblasts, found in tendons and ligaments that connect muscles, bones, and organs
supporting - firm extracellular tissue, bone, and cartilage
fluid - cells are surrounded by fluid extracellular matrix-ECM = plasma, blood
nervous tissue
nerve cells are neurons and then supporting cells only appear in neurons
neurons - transmit electrial signal, 2 projections from cell body
dendrites - highly branched, short - facilitate transmission of signals from adjacent cells to nerual cell body
axon - long, carries electrical signal from cell body to other cells
glia - supporting cells
cns - oligodendrocytes
pns - schwann cells
muscle tissue
only in animals, functions in movement, pumping of blood, mixing food
skeletal - connect bones and cause body movement
cardiac - make up walls, heart, and pump blood
smooth muscle - lines walls of digestive tract, blood vessels, move food, regulate blood pressure
epithelial tissue
covers outside of body, line inner surface of many organs, form glands, short lived
esophogus 2-3 days and large intestine 6
gland - organ that secretes specfic molecules or solutions
apical side - face environment
basolateral side - face animal’s interior and connects to connective tissue
Surface area: volume
ratio affects animal physiology
surface area - affects rae of diffusion
volume - determines the rate at which nutrients are used and waste generates
metabolic rate
overall rate of energy consumption
measured by rate of oxygen consumption - mL 02 consumed per hour
basal metabolic rate BMR
rate animal consumes oxygen, while at rest
mass specfic BMR
function of body mass
mL of O2 consumed per gram of body mass per hour
small animals have —- BMR’s than large anddd as the organisms size —— mass specific metabolic rate decreased
higher BMR’s, and as size increases
homeostasis
occurs when the system is optimal, stabile in chemical and physical conditions within organisms cells, tissue, organs//// maintains constant internal conditions— enzymes and other cellular process-diffusion- function best at certain temps, pH, etc
homeostatis steps
conform - maintain internal close to environment
physiological regulation - expends energyto maintain internal state even when envi fluctuates
behavioral regulation - regulates internal state by changing behavior
need to do a little of all
regulation
system is regulating levels/ concentrations kept constant by balancing influx and efflux if it doesn’t match it fails
advantages - lower energy costs, no regulatory system needed, greater ability to tolerate a range of conditions, greater capacity for activity in a range of conditons
disadvantages - less ability to tolerate a range of conditions, energetically expensive, must have evolved regulatory systems, reduced ability to regulate - can only when envi is right
influx
in
efflux
out
set point
normal range of values for controlled variable
sensor
structure senses the environment
integrator
compare incoming sensory info to set point and determines whether response is needed
effector
structure helps restore internal conditions
this alllll maintains
a negative feedback loop, effectors oppose direction of change in internal state
thermoregulator
maintains temp requires balancing heat influx and efflux
PICTURES IN PHOTOS CHECK!!
conduction
direct transfer of heat between two physical bodies in contact with each other
convection
heat exchange between solid and liquid or gas-fluid flow
radiation
transfer heat between 2 bodies not in direct physical contact
evaporation
phase exchange occurs when liquid water becomes gas
metabolism
heat is a byproduct of biochemical activity
endotherm
produces enough heat to warm own tissues
warm themselves due to high basal metabolic rate which leads to move active all time and ATP costly, retain heat-insulation fur and heat,
ectotherm
relies on heat gained from environment
low ATP/food intake so greater ATP supporting reproduction
homeotherm
keeps body temp constant
poikilotherm
allows body to rise and fall on environment
maintain heat/ reducing heat efflux
reduces surface area, increase insulation - trap still air in fur and feathers and being fat if there are no fur/feathers
decrease temperature differential
use torpor - drop in body temp for a week or 2 - or hibernation - long drop in body temp - reduces overall body temp
countercurrent exchange to reduce heat of blood in extremities— IN PHOTOS
asexual reproduction
mitosis, without fusion of gametes, offspring are same as parent
sexual reproductin
meiosis, fusion of gametes
budding
offspring forms wihin or on the parent then breaks free and grows on its own
fission
individual splits into 2 or more descendants
parthenogenesis
female produces an offspring without help from a male —-mitosis, meiosis, or fusion of two products of meiosis
most animals produce
sexually, haploid gametes fuse to form diploid offspring—increase chance that offspring will do well if more variable, increased chance of successful genotype - physical conditions, predator/prey interactions, disease
why some are asexual repro
have the advantage every individual generates offspring, pass 100% of alleles - sexual parents only 50%
daphnia - water flea
spring/summer
produce diploid female offspring with parthenogenesis - which develop a brood pouch, offspring released when it molts
late summer/fall
many develop into males which produce sperm by meiosis and females eggs by meiosis - sperm → egg
fertilized eggs fall to bttm of lake overwinter in spring eggs hatch as female
the switch is caused by
environmental cues - water quality as crowded, food concentration low, day length = short
need all 3 conditions
gametogenesis
production of male and female gametes
gametes
haploud cell that animals form by meiosis of diploid cells
spermatogenesis
males produce 4 sperms from each diploid spermatogonium celll
oogenesis
females produce only 1 egg-ovum- from each diploid oogonium —other 3 become polar bodies
external fertilization
aquatic environments, large amount of gametes, gametogenesis occurs in response to envi cues like day lengthing and warmer temps, chemical messangers-pheromones - involve coordination
-spawning - selection and localized
broadcasting fertilization - non-selective, pop wide release of gametes
internal fertilization
occurs terrestrial and aquatically, mostly terrestr.
sperm can be packaged into a spermatophore that is left by the male and picked up by the female
-male salamander deposits the spermatophore on the ground and the female picks it up with her cloaca - sperm can be deposited directly in females - humans =copulation
competition that occurs after mating between sperm from different males to fertilize the eggs of the same female —-
in many animals - females mate with multiple males
sperm deposited by a 2nd male may displace sperm stored from earlier matings - 2nd-male adv is widespread but not universal in insects and some others
male w larger testes produce more sperm and increase the odds of successfully fertilizing eggs, female may choose mate order or physically eject sperm from undesireable mates
male genitalia
certain shapes may give them a sperm competitive adv, natural selection that occurs during sperm competition may explain why is it so diverse among insects/spiders, some genera of spider, species are id’d by gentalia shape
seed beetles
males w longer spines on the tip of their genitalia were more succesful in copulating with females
fitness trade-off
compromise between traits,
ex: spermatophore in crickets - which is a packet of sperm surrounded by gelatinous mass, male deposits that on the female genital opening, females eat mass after mating-longer it takes, more sperm from male fertilize eggs — larger spermatophore=more success per mating, it is costly and takes more than 3 hours to make — larger spermatophore=less time spent mating
development can be internal or external
oviparous and can result in either internal or external fert.
vivparous is internal and embryo cont. exchanges material w mother
ovoviviparous - internal but within a yolk-filled egg
animals use 2 main mechanisms to carry messagees to and from control centers
neural signals- action p, neurvous system
faster, more specficially targeted, short
chemical signal - horomones, endocrine system
slower, more broad, but longer lasting
crin
seperated
autocrine
act on same cell that secretes them —cytokines
paracrine
diffuse locally and act on nearby cells
endocrine
hormones carried between cells by blood or other body fluids
endocrine system
collection of organs and cells that secrete chemical signals into blood stream —through glands
hormones
chemical signal that circulates through body fluid and affects distant targets, present in low concentratiosn
neural
neurotransmitters, short lived, diffuse a short distance between neurons
neuroendocrine
neurohormones, hormones released from neurons, bc carried by blood or body fluid to act on distant cells
ex: ADH-antidiuretic horomone - regulate water in collecting duct of kidney, produced by hypothalamus
insulin and glucagon
act as paracrine, but also hormone, produced in pancreas,
panacrine - when on nearby pancreatic cells to ensure steady response to changing blood glucose levels
hormone - released into blood controlling concentration of glucose in blood
exocrine
release fluids through ducts into space other than circulatory system
some gland are endocrine, exocrine, or both
exocrine - salivary glands, sweat glands, mammary glands
both - pancreas
endocrine pathway
endocrine cells respond directly to an environmental signal by secreting a hormone
photo
neuroendocrine pathway
info about exteranl condition is gathered and integrated by neurons in CNS, neurons produce a hormone-neurohormone- which acts on effector cells or ——
neuroendocrine to endocrine pathway
info about external is gathered and integrated by neurons in the CNS, which produce hormone- neurohormone- acts on effector cells or stimulates cells in endocrine system to produce hormones
hormone receptors
responses required appropriate receptors — membrane-bound receptors — which activate or de biochemical pathways
hormone class 1 - peptides and polypeptides
chain of amino acids, bind to receptors on plasma membrane - not lipid soluble
hormone 2 - amino acid derivative
ex: epinephrine/adrenaline, thyroid hormones -lipid soluble, generally most not lipid soluble and bind to receptors on surface of target cell
hormone 3 - steroids
lipid soluble bind to receptors inside target cell, target intracellular receptors, ex: estrogen
hormones have 3 major classes^^
key difference in solubility
signal transduction
message must be transduced to insde the cell
target cells w/ same receptor protien may have
different second messenger or enzyme system
same hormone and receptor can give rise to
different response in different target cells
same chemical messengers can trigger
different responses in cells from different organs or cells at different developmental stages
single hormone can exert a variety of effects
triiodothyronine - T3 and thyroxine - T4 are produced by the thryoid gland - stimulate metabolism, promot growth, increase heart rate, and stimulate synthesis of macromolecules/proteins
several different hormones may affect same aspect of physiology
insulin, glucagon, epinephrine all influence glucose levels in the blood
hormones coordinate cells activity in
development, growth, and repro
response to envi challenge
maintain homeostasis
thryoid hormone in amphibian metamorphosis
signal from brain, pituitary gland secretes thryoid-stimulating hormone - TSH, which stimulates thyroid to produce T4, converted to T3 at target tissue, juvenile amph. T3 stimulates growth of new structures-legs
known from an experiement - that it is from thryoid hormone
growth and metamorphosis insects involves
juvenile hormone -JH
ecdysone - ecdysis-molting
high JH+ecdysone surge = larval grwoth - molting
low JH + ecdysone surge = pupation and metamorphosis
short - term = fight or flight
triggered by cns sympathetic nervous system whcih stimulates adrenal gland to release epinephrine
photo - heart-increase cardiac output, blood vessels - increase flow to muscles, heart, brain, liver - increase glucose release, fat cells- increase fat release
longer term - sustained by activity and alertness increase
stress response, driven by cortisol
photo - hypothalamus produces increase in corticotropin releasing hormone through the anterior pituitary - which increased adrenocorticotropic hormone in the adrenal gland which increase cortisol release —- then liver - more conversion of protein to glucose, fat cells - increase release, immune system - decreases
maintaing homeostasis
messages from integrators to effectors are often sent through hormones
ex: blood glucose — too low - not enough fuel for brain —too high - toxic = organ failure
blood glucose homeostasis
eating - rises blood glucose levels - stimulates release of insulin which stimulates effector cells in body to import glucose from blood for storage or metabolism use - blood glucose levels drop
hours after meal - blood glucose levels decline as glucose goes to cellular resp, glucagon - released from pancreas - causes glucose sotring cels in liver to export glucose to blood - -blood glucose levels increase
PHOTOS
water and electrolyte balance— dehydrated
dehydrated - ADH-antidiuretic released by pituitary which increase permeability of kidney’s collecting ducts to water - so waters reabsorbed through urine
ethanol-alcohol —-inhibits release of ADH so large dilute urine, lots of dehydration
water and electrolyte balance - good hydration
aldosterone - released from adrenal cortex when sodium concentrations in body fluids are low, Na+/K+ pumps active- result in increased reabsorp of sodium ions in distal tubules of kidney - adrenal hormones thatfunction in regulating electrolyte balance are called mineralcorticoids
hypersecretion
too much hormone secreted - hyperthryoidism - overheat, weight loss, restlessness
hyposecretion
too little hormone secreted - type 1 diab - lack of insulin so fails to metabolize and store glucose from meals
hyporesponsiveness
too few hormone receptors- type 2 diab - lack insulin recep lead to milder type 1 effects
multi-hormone pathways probs w upstream hormones cause
probs w downstream hormones
negative feedback loops
hormones control effectors that influnce a varibale - value of that variable helps determine amount of hormone released
short-loop feedback - hypothalamic-pituitary axis
levels of downstream have negative effects on levels of upstream - - feedback inhibition
PHOTOS
nervous system does
gather info about exter + intern envi, activates skeletal muscles and endocrine glands, influences activity of smooth muscles in GI tract and arterioles, influences heart rate, integrates info and makes decisions
nerve net
diffuse arrangement of cells
central nervous system
large number of neurons aggregated into clusters- ganglia
cns
brain - higher level decison making + control
brainstem - influences heart, ventilation, digestio
spinal cord - transmit info, some reflexes
pns
all neurons and other components not in CNS
afferent - sensory = brings sensory to cns
efferent - motor = carries CNS to effectors
somatic ns
autonomic ns - symp and parasymp
somatic ns
voluntary response, skeletal muscles=effectors
autonomic ns
involuntary response, smooth, cardiac muscles, and glands =effectors
sympathetic- fight or flight, increases physical activity, inhibit digestion
parasympathetic - rest and digest, promote digestion reduce activity
PHOTOS