CPPS 304 FORMULAS
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6 Terms
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half-life t1/2
t1/2=(0.693xVd) divided by CL
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Plasma Clearance (CLp)
CLp = (Rate of elimination from plasma) divided by (concentration of drug in plasma)
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Clearance (CL)
CL= (0.693 x Vd) divided by t1/2
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clearance (using AUC) (CL)
CL = (dose) divide by (Area Under Curve)
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Loading dose (LD)
LD= (target plasma concentration [Cp] x Vd) divided by (bioavailability [F])
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Maintenance dose (Md)
Md = (target plasma concentration [CP] x CL) divided by (bioavailability [F])
Note 
Flashcards (40)