Vitamin D Synthesis
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7 Terms
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What is the first step of vitamin D synthesis?
7-Dehydrocholestrol -> Cholecalciferol (Ergocalciferol/plants)
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What is needed to convert 7-Dehydrocholestrol -> Cholecalciferol?
UV Light
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Second step of vitamin D synthesis
Cholecalciferol -> 25-Hydroxycholecalciferol (calcidiol)
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What enzyme is needed for the second step?
25' hydroxylase (liver)
5
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Third step of vitamin D synthesis
25-Hydroxycholecalciferol (calcidiol) -> 1-25-dihydroxycholeclacifierol (calcitriol) (active VD)
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What enzyme is needed for the third step?
1'-a-hydroxylase (kidney)
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Final step of vitamin D synthesis
1-25-dihydroxycholecalciferol (calcitriol) (active VD) -> intestinal cell
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