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steroids, nonsteroids
What are the two types of hormones?
lipids
Are steroids lipids or proteins?
proteins
Are nonsteroids lipids or proteins?
G protein
Which intracellular protein activates the enzyme adenylate cyclase?
adenylate cyclase
Which enzyme forms cAMP from ATP?
protein kinases
What set of enzymes are active in the phosphorylation of protein substrates after the formation of cAMP?
protein kinases
What does cAMP activate?
tropic hormones
What are hormones that work on other glands called?
negative feedback
What kind of feedback maintains the homeostasis of most hormone levels?
hypophysis
What is another name for the pituitary gland?
infundibulum (pituitary stalk)
What attaches the pituitary gland to the hypothalamus?
adenohypophysis
What is another name for the anterior lobe of the pituitary gland?
neurohypophysis
What is another name for the posterior lobe of the pituitary gland?
growth, thyroid-stimulating, adrenocorticotropic, follicle-stimulating, luteinizing, prolactin
Which hormones does the anterior lobe of the pituitary gland secrete?
antidiuretic hormone (ADH), oxytocin (OT)
What hormones are secreted by the posterior lobe of the pituitary gland?
glandular cells
What type of cells make up the anterior lobe of the pituitary gland?
prolactin
Which protein promotes milk production?
zona glomerulosa
Which is the outermost layer of the adrenal cortex?
zona fasciculata
What is the middle layer of the adrenal cortex?
zona reticularis
What is the innermost layer of the adrenal cortex?
thyroxine, triiodothyronine, calcitonin
Which 3 hormones are produced by the thyroid?
thyroxine, triiodothyronine
Which hormones are secreted by the follicular cells of the thyroid?
calcitonin
Which hormone is secreted by the extrafollicular cells of the thyroid?
parathyroid hormone (PTH)
Which hormone do the parathyroid glands secrete?
adrenal medulla
What is the core of the adrenal gland called?
kidneys
The adrenal glands are found on top of what organs?
epinephrine, norepinephrine
Which hormones are produced, stored, and secreted by the adrenal medulla?
aldosterone, cortisol, sex hormones
Which hormones are secreted by the adrenal cortex?
glucagon, insulin, somatostatin
Which hormones are secreted by the pancreatic islets?
melatonin
Which hormone does the pineal gland secrete?
thymosins
Which hormones are released by the thymus?
phosphodiesterase
Which enzyme inactivates cAMP?
paracrine
Which secretions only affect nearby cells?
autocrine
Which secretions only affect the cell itself?
glandular epithelium
What are the cells of the endocrine system called?
second
cAMP is a _____ messenger
first
A non-steroid hormone is a _____ messenger.
phosphodiesterase
Which enzyme shuts down cAMP by breaking its circle?
oxytocin
Which hormone signals the breasts to release milk and the uterus to contract?
Pitocin
What is the synthetic form of oxytocin?
thyroid
Which gland needs iodine?
simple cuboidal epithelial cells
What type of cells make up the thyroid follicles?
iodine, thyroglobulin
What does the colloid of thyroid follicular cells contain?
triiodothyronine
Which hormone is active and is 5% of hormones released from thyroid?
thyroxine
Which hormone is a reserve and 95% of hormones released from thyroid?
extrafollicular cells of thyroid (C cells)
Which cells tastes blood for high calcium levels?
parathyroid glands
Which glands taste blood for low calcium levels?
parathyroid hormone
Which hormone raises calcium levels in blood?
glucokinase
Which enzyme is sensitive to high blood sugar and triggers the production of insulin?
glucagon
Which hormone do alpha cells release?
insulin
Which hormone do beta cells release?
somatostatin
Which hormone do delta cells release?
gluconeogenisis
What is the process that converts non-carbohydrates in to carbohydrates?
ketoacidosis
What is the condition of being acidic due to ketones?
zona reticularis
Which layer of the adrenal gland releases sex androgens (testosterone)?
zona fasciculata
Which layer of the adrenal gland releases cortisol?
zona glomerulosa
Which layer of the adrenal gland releases aldosterone?
endocrine glands
glands that synthesize and secrete hormones into the bloodstream
exocrine glands
secrete chemical substances into ducts that lead either to other organs or out of the body
corticosteroids
A group of hormones, including cortisol, released by the adrenal glands at times of stress
transcortins
proteins that transport corticosteroids
glucocorticoids
Stress hormones that increase energy production
by triggering gluconeogenesis to raise blood glucose levels
cortisol, cortisone
name 2 glucocorticoids
mineralocorticoids
stress hormones that increase blood volume and blood pressure by regulating plasma levels of sodium and potassium
aldosterone
name 1 mineralocorticoid
angiotensin II
aldosterone is stimulated by _____
ANP (atrial natriuretic peptide)
aldosterone is inhibited by _____
catecholamines
hormones derived from an amino acid and secreted by the adrenal medulla, such as epinephrine and norepinephrine
luteinizing
which hormone stimulates ovaulation?
luteinizing
which hormone maintains the corpus luteum?
luteinizing
which hormone regulates progesterone secretion in women?
luteinizing
which hormone stimulates the interstitial cells of the testes to synthesize testosterone?
follicle-stimulating
which hormone causes maturation of ovarian follicles?
estrogen
ovarian follicles secrete _____
follicle-stimulating
hormone that stimulates maturation of seminiferous tubules and sperm production
endorphins
neurotransmitters that have pain-relieving properties
somatotrophin
another name for growth hormone
acromegaly
a disorder characterized by a disproportionate overgrowth of bone, especially in the skull, jaw, feet, and had
melanocyte-stimulating hormone
hormone secreted by the intermediate lobe of the pituitary; in frogs it causes darkening of the skin
oxytocin
hormone that increases the strength and frequency of uterine muscle contractions
oxytocin
stimulates milk secretion in the mammary glands; induced by suckling
vasopressin
another name for antidiuretic hormone
neurosecretory cells
cells that regulate pituitary gland secretions via negative feedback mechanisms and through the actions of inhibiting and releasing hormones
GnRH
hormone that stimulates the anterior pituitary to secrete FSH and LH
corticotropin-releasing factor (CRF)
cells release _____ into the portal system, which signals the pituitary cells to release ACTH
cretinism
hypothyroidism in infants; characterized by mental retardation and short stature
islets of Langerhans
cell clusters in the pancreas that form the endocrine part of that organ
erythropoietin
a glycoprotein that stimulates red blood cell production
gastrin
Hormone that the stomach lining secretes to simulate gastric juice
secretin
released by small intestine when chyme enters from stomach; stimulates the secretion of an alkaline bicarbonate solution from the pancreas that neutralizes the acidity of the chyme
cholecystokinin
released by the small intestine in response to the presence of fats and causes the contraction of the gallbladder and release of bile into the small intestine
peptides
nonsteroid hormones are also known as _____
first
peptides are _____ messengers